Psoriasis and Cardiovascular Diseases: A Literature Review to Determine the Causal Relationship

Shanu Jindal1, Nitin Jindal2

  • 1Public Health Education, University of North Carolina-Greensboro.

Cureus
|April 18, 2018
PubMed

Insights

Psoriasis patients face a higher risk of cardiovascular diseases (CVD). This review confirms a significant association, highlighting the need for comprehensive patient management.

Area of Science:

  • Dermatology
  • Cardiology
  • Immunology

Background:

  • Psoriasis is a chronic autoimmune skin condition.
  • It affects skin and joints in about one-third of patients.
  • An association between psoriasis and cardiovascular diseases (CVD) is increasingly recognized.

Purpose of the Study:

  • To review the existing literature on the association between psoriasis and CVD.
  • To evaluate the evidence supporting an increased cardiovascular risk in psoriasis patients.

Main Methods:

  • Extensive literature review.
  • Adherence to Gordis guidelines for evidence assessment.

Main Results:

  • Psoriasis is linked to a higher risk of cardiovascular morbidity.
  • Patients with psoriasis exhibit a greater prevalence of cardiovascular risk factors.
  • A positive association between psoriasis and cardiovascular events is demonstrated.

Conclusions:

  • Psoriasis is associated with an increased risk of cardiovascular events.
  • This underscores the importance of considering cardiovascular health in psoriasis management.

Related Concept Videos

Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
582
Causality in Epidemiology01:21

Causality in Epidemiology

Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...
1.7K
Relationship Formation02:12

Relationship Formation

What do you think is the single most influential factor in determining with whom you become friends and whom you form romantic relationships? You might be surprised to learn that the answer is simple: the people with whom you have the most contact. This most important factor is proximity. You are more likely to be friends with people you have regular contact with. For example, there are decades of research that shows that you are more likely to become friends with people who live in your dorm,...
46.3K
Review and Preview01:10

Review and Preview

In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
8.4K
Review and Preview01:13

Review and Preview

Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.6K
Ending Relationships01:28

Ending Relationships

The dissolution of intimate relationships presents complex emotional and psychological challenges, particularly when emotional bonds are strong, the relationship is long-standing, and perceived alternatives are limited. This distress often intensifies in romantic breakups, where the initiator may experience greater turmoil than the rejected partner. Contributing factors include residual attachment, guilt over causing pain, and uncertainty about how to manage the situation. The stress is further...
205