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Generation of Porcine Testicular Organoids with Testis Specific Architecture using Microwell Culture
Published on: October 3, 2019
Successful onco-testicular sperm extraction from a testicular cancer patient with a single testis and azoospermia
Shinnosuke Kuroda1, Takuya Kondo1, Kohei Mori1
1Department of Urology, Reproduction Center, Yokohama City University Medical Center, Yokohama, Japan.
Abstract:
Onco-testicular sperm extraction is used to preserve fertility in patients with bilateral testicular tumors and azoospermia. We report the case of a testicular tumor in the solitary testis of a patient who had previously undergone successful contralateral orchiectomy and whose sperm was preserved by onco-testicular sperm extraction. A 35-year-old patient presented with swelling of his right scrotum that had lasted for 1 month. His medical history included a contralateral orchiectomy during childhood. Ultrasonography revealed a mosaic echoic area in his scrotum, suggesting a testicular tumor. The lesion was palpated within the normal testicular tissue along its edge and semen analysis showed azoospermia. Radical inguinal orchiectomy and onco-testicular sperm extraction were performed simultaneously. Motile spermatozoa were extracted from normal seminiferous tubules under microscopy and were frozen. Eventual intracytoplasmic sperm injection using the frozen spermatozoa is planned. Onco-testicular sperm extraction is an important fertility preservation method in patients with bilateral testicular tumors or a history of a previous contralateral orchiectomy.
Insights
Onco-testicular sperm extraction successfully preserved fertility in a patient with a solitary testicular tumor and azoospermia. This technique is vital for men with bilateral testicular tumors or prior orchiectomy, safeguarding future reproductive options.
Area of Science:
- Reproductive Medicine
- Oncology
- Urology
Background:
- Fertility preservation is crucial for cancer patients.
- Onco-testicular sperm extraction is a method for patients with bilateral testicular tumors and azoospermia.
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