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Author Spotlight: Unveiling Mechanisms of Stress Resilience - Significant Findings, Advancements, and Future Research
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Reduced Orexin System Function Contributes to Resilience to Repeated Social Stress

Laura A Grafe1, Darrell Eacret1, Jane Dobkin2

  • 1Department of Anesthesiology and Critical Care, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104.

Eneuro
|April 18, 2018
PubMed
Summary

Lowering orexin neuropeptides promotes resilience to social stress. This research suggests that targeting orexin levels may offer a novel therapeutic strategy for stress-related disorders like depression and PTSD.

Keywords:
Anxiety and depressionDREADDshypocretinresiliencesocial defeatvulnerability

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