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[Thyroid ectopia and Basedow's disease].

A Azzam1, N Nitunga, J L Baulieu

  • 1Service de Médecine B, Endocrinologie, CHU Bretonneau, Tours.

Presse Medicale (Paris, France : 1983)
|March 5, 1988
PubMed
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Graves' disease, a rare autoimmune thyroid condition, was diagnosed in a woman with an ectopic subhyoid thyroid gland. This case highlights the infrequent occurrence of Graves' disease in such anatomical variations.

Area of Science:

  • Endocrinology
  • Thyroidology
  • Autoimmune Diseases

Background:

  • Graves' disease is an autoimmune disorder characterized by hyperthyroidism.
  • Ectopic thyroid tissue can occur in various locations, posing diagnostic challenges.
  • Thyroid abnormalities in childhood, such as myxoedema, can sometimes be associated with later thyroid conditions.

Observation:

  • A 35-year-old woman with a history of childhood myxoedema presented with symptoms of Graves' disease.
  • Diagnostic evaluations including clinical assessment, ultrasonography, and radioisotope scanning were performed.
  • The investigations revealed the presence of an ectopic subhyoid thyroid gland.

Findings:

  • Graves' disease was diagnosed in the patient, with the thyroid gland located ectopically in the subhyoid region.

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  • This represents a rare presentation, as Graves' disease associated with ectopic thyroid tissue is infrequently reported.
  • The patient's history of childhood myxoedema may be relevant to the development of this condition.

    • Implications:

    • This case underscores the importance of considering ectopic thyroid tissue in the differential diagnosis of thyroid disorders, even in the presence of typical Graves' disease symptoms.
    • The rarity of Graves' disease in ectopic thyroid glands suggests potential unique pathophysiological mechanisms or genetic predispositions.
    • Further research into the association between ectopic thyroid glands and autoimmune thyroid diseases like Graves' disease is warranted to understand the underlying factors and improve clinical management.