Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Protein Complex Assembly02:41

Protein Complex Assembly

16.9K
Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...
16.9K
Protein Complexes with Interchangeable Parts01:57

Protein Complexes with Interchangeable Parts

2.9K
Groups of proteins may form a complex where each protein in this complex has a different role in the overall execution of the complex’s function. Often some of the proteins in the complex can be replaced by a closely related variant to give a complex that contains many of the same components yet is functionally distinct.
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order...
2.9K
Complex Numbers01:29

Complex Numbers

324
The real number system cannot represent the square root of a negative number, which restricts solutions for certain equations, such as quadratics with negative discriminants. To address this, the complex number system was developed, introducing the imaginary unit i, where i = √(-1). This extension allows for the representation of all roots, including those involving negative radicands.A complex number is written in the form x + yi, where x and y are real numbers. Here, x represents the...
324
Formation of Complex Ions03:45

Formation of Complex Ions

26.2K
A type of Lewis acid-base chemistry involves the formation of a complex ion (or a coordination complex) comprising a central atom, typically a transition metal cation, surrounded by ions or molecules called ligands. These ligands can be neutral molecules like H2O or NH3, or ions such as CN− or OH−. Often, the ligands act as Lewis bases, donating a pair of electrons to the central atom. These types of Lewis acid-base reactions are examples of a broad subdiscipline called coordination...
26.2K
Complex Power01:14

Complex Power

929
Power engineers have introduced the concept of complex power to determine the cumulative effect of parallel loads. This idea plays a crucial role in power analysis because it encompasses all the details related to the power consumed by a specific load.
Complex power is defined as the multiplication of the voltage and the complex conjugate of the current. The magnitude of this power, known as apparent power, is measured in volt-amperes (VA). Notably, the angle of the complex power equates to the...
929
Complexation Equilibria: Factors Influencing Stability of Complexes01:09

Complexation Equilibria: Factors Influencing Stability of Complexes

868
In complexation reactions, metal cations are the electron pair acceptors, and the ligands are the electron pair donors. The stability of the metal complexes depends primarily on the complexing ability of the central metal ion and the nature of the ligands. Generally, the complexing ability of the metal ion depends on the size and charge of the ion. As the metal ion size increases, the stability of the metal complexes decreases, provided that the valency of the metal ion and the ligands remain...
868

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Current Landscape of Clinical Interventions for Trigeminal Neuralgia: A Scoping Review.

Pain management nursing : official journal of the American Society of Pain Management Nurses·2026
Same author

Neuroplacental Interactions in early human development: Insights from selective acute neuronal necrosis.

Placenta·2026
Same author

Brain-wide mapping of developmental trajectories of cerebellar efferent projections.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Multiple parallel cell lineages in the developing mammalian cerebral cortex.

Science advances·2024
Same author

Input-dependent segregation of visual and somatosensory circuits in the mouse superior colliculus.

Science (New York, N.Y.)·2022
Same author

Uncoupling axon guidance and neuronal migration in Robo3-deficient inferior olivary neurons.

The Journal of comparative neurology·2022

Related Experiment Video

Updated: Feb 11, 2026

Ex Vivo Oculomotor Slice Culture from Embryonic GFP-Expressing Mice for Time-Lapse Imaging of Oculomotor Nerve Outgrowth
06:04

Ex Vivo Oculomotor Slice Culture from Embryonic GFP-Expressing Mice for Time-Lapse Imaging of Oculomotor Nerve Outgrowth

Published on: July 16, 2019

9.1K

The Amniote Oculomotor Complex.

Verónica Company1, Juan Antonio Moreno-Bravo1,2, Ariadna Perez-Balaguer1

  • 1Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-CSIC, Sant Joan d'Alacant, Alicante 03550, Spain.

Anatomical Record (Hoboken, N.J. : 2007)
|April 18, 2018
PubMed
Summary
This summary is machine-generated.

The oculomotor (OM) complex, crucial for eye movements and pupil control, requires precise development. This study details OM neuron organization, signaling, and genetic guidance mechanisms, highlighting links to strabismus and other developmental disorders.

Keywords:
Peripheral nervous systemclinical anatomycranial nerve nucleioculomotor nucleussegmental organization

More Related Videos

Lumican Extraction from Amniotic Membrane and Determination of its Storage Temperature
04:21

Lumican Extraction from Amniotic Membrane and Determination of its Storage Temperature

Published on: October 14, 2022

1.8K
Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model
06:43

Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model

Published on: October 9, 2018

10.2K

Related Experiment Videos

Last Updated: Feb 11, 2026

Ex Vivo Oculomotor Slice Culture from Embryonic GFP-Expressing Mice for Time-Lapse Imaging of Oculomotor Nerve Outgrowth
06:04

Ex Vivo Oculomotor Slice Culture from Embryonic GFP-Expressing Mice for Time-Lapse Imaging of Oculomotor Nerve Outgrowth

Published on: July 16, 2019

9.1K
Lumican Extraction from Amniotic Membrane and Determination of its Storage Temperature
04:21

Lumican Extraction from Amniotic Membrane and Determination of its Storage Temperature

Published on: October 14, 2022

1.8K
Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model
06:43

Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model

Published on: October 9, 2018

10.2K

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Anatomy

Background:

  • The oculomotor (OM) complex integrates somatic and parasympathetic neurons essential for eye and eyelid movements, pupillary constriction, and lens accommodation.
  • Proper development and function of the OM complex are critical; malformations can lead to pathologies like strabismus.

Purpose of the Study:

  • To describe the organization and function of the OM complex across vertebrate brains (chick, mouse, human).
  • To clarify the morphological localization and spatial relationship with the trochlear nucleus, correcting anatomical misconceptions.
  • To detail signaling pathways and transcriptional programs involved in OM neuron specification, differentiation, migration, axon pathfinding, and targeting.

Main Methods:

  • Comparative morphological analysis of OM complex organization in chick, mouse, and human brains.
  • Review of genetic studies identifying guidance mechanisms for OM neuron development.
  • Overview of pathologies associated with genetic malformations in OM development.

Main Results:

  • Detailed description of OM complex morphology and its topographic relation to the trochlear nucleus.
  • Identification of key signaling processes and transcriptional programs governing OM neuron specification and differentiation.
  • Summary of genetic factors influencing OM neuron migration, axon guidance, and target innervation.

Conclusions:

  • Understanding OM complex development is vital for comprehending normal ocular function and associated pathologies.
  • This review consolidates current knowledge on OM neuron development, providing a foundation for future research into related clinical conditions.
  • Accurate anatomical and developmental insights into the OM complex are crucial for diagnosing and potentially treating strabismus and other related disorders.