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Intraspinal intradural nodular fasciitis mimicking glioblastoma metastasis: a case report

Carl Moritz Zipser, Lars Füllbier, Rudi Beschorner

    Folia Neuropathologica
    |April 18, 2018
    PubMed

    Insights

    A glioblastoma patient developed spinal issues, but surgery revealed nodular fasciitis, not cancer metastasis. This case highlights the importance of histopathology in diagnosing spinal lesions.

    Area of Science:

    • Neuro-oncology
    • Neurosurgery
    • Neuropathology

    Background:

    • Glioblastoma is an aggressive primary brain tumor.
    • Meningeal tumor spread can occur in glioblastoma.
    • Spinal cord compression requires urgent diagnosis and management.

    Observation:

    • A 78-year-old male with right temporal glioblastoma presented with paraplegia.
    • MRI revealed an intraspinal intradural lesion compressing the spinal cord.
    • Initial suspicion was spinal metastasis from glioblastoma.

    Findings:

    • Emergency spinal decompression and mass resection were performed.
    • Histopathology confirmed nodular fasciitis, not glial tumor metastasis.
    • This diagnosis ruled out a direct spinal spread of glioblastoma.

    Implications:

    • Accurate histopathological diagnosis is crucial for spinal lesions, even with suspected cancer spread.
    • Nodular fasciitis can mimic spinal metastasis, necessitating careful evaluation.
    • This case underscores the differential diagnosis challenges in neuro-oncology and neurosurgery.
    Keywords:
    acute paraplegiamyelon compressionnodular fasciitisspinal metastasisglioblastoma

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