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Clinical problems in hemodialysis patients with autosomal dominant polycystic kidney disease
Ismail Kocyigit1, Eray Eroglu1, Ozkan Gungor2
1Department of Nephrology, Erciyes University Medical Faculty, Kayseri, Turkey.
Insights
Autosomal dominant polycystic kidney disease (ADPKD) is a genetic kidney disorder causing large cysts. This review focuses on managing ADPKD complications in hemodialysis patients.
Area of Science:
- Nephrology
- Genetics
- Internal Medicine
Background:
- Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited kidney disorder.
- It leads to massive kidney cyst enlargement and is a leading cause of chronic kidney disease (CKD).
- ADPKD is a multi-system disorder associated with hypertension and cardiovascular/cerebrovascular events.
Purpose of the Study:
- To review specific clinical problems encountered in ADPKD patients undergoing hemodialysis.
- To discuss current management strategies for these clinical issues.
Main Methods:
- Literature review of clinical problems and management in ADPKD patients on hemodialysis.
- Synthesis of information on disease-specific complications and therapeutic approaches.
Main Results:
- ADPKD presents unique clinical challenges in hemodialysis patients.
- Management requires addressing systemic complications alongside kidney disease progression.
Conclusions:
- Effective management of ADPKD in hemodialysis patients necessitates a comprehensive approach.
- Addressing hypertension, cardiovascular, and cerebrovascular complications is crucial for patient outcomes.
Abstract:
Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenic disease characterized by massive enlargement of fluid-filled cysts in the kidney. Due to its genetic pattern, the disease differs from other CKD. ADPKD is a multi-system, progressive disorder which is frequently complicated with hypertension, cardiovascular events and cerebrovascular disease. Thus, there are many clinical problems specific to ADPKD. In this article, we reviewed these clinical problems and their management in ADPKD with hemodialysis patients.
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