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Prevalence and Incidence01:08

Prevalence and Incidence

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In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
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Types of Reports II: Incident or Occurrence Report01:21

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An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
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Cerebral Hemispheres01:05

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The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
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Nondisjunction01:29

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During meiosis, chromosomes occasionally separate improperly. This occurs due to failure of homologous chromosome separation during meiosis I or failed sister chromatid separation during meiosis II. In some species, notably plants, nondisjunction can result in an organism with an entire additional set of chromosomes, which is called polyploidy. In humans, nondisjunction can occur during male or female gametogenesis and the resulting gametes possess one too many or one too few chromosomes.
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Bystander Effect02:09

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The discussion of bullying highlights the problem of witnesses not intervening to help a victim. This is a common occurrence, as the following well-publicized event demonstrates. In 1964, in Queens, New York, a 19-year-old woman named Kitty Genovese was attacked by a person with a knife near the back entrance to her apartment building and again in the hallway inside her apartment building. When the attack occurred, she screamed for help numerous times and eventually died from her stab wounds.
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What is a Sensory System?01:31

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Sensory systems detect stimuli—such as light and sound waves—and transduce them into neural signals that can be interpreted by the nervous system. In addition to external stimuli detected by the senses, some sensory systems detect internal stimuli—such as the proprioceptors in muscles and tendons that send feedback about limb position.
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Related Experiment Video

Updated: Feb 11, 2026

Calcified Artery Preparation and Processing with Preserved Morphology and RNA for Digital Spatial Profiling
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Calcified Artery Preparation and Processing with Preserved Morphology and RNA for Digital Spatial Profiling

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Calcified cerebral emboli: Incidence and implications.

Miguel Bardon1, Julian Hanson1, Bill O'Brien1

  • 1Gosford Hospital, Gosford, New South Wales, Australia.

Journal of Medical Imaging and Radiation Oncology
|April 18, 2018
PubMed
Summary

Calcified cerebral emboli are a common cause of ischemic stroke, often overlooked. This study found they account for 5.9% of strokes, highlighting their clinical importance for diagnosis and treatment.

Keywords:
adult neuroimagingneurointerventional radiologyneuroradiologyvascular imaging

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Area of Science:

  • Neurology
  • Radiology
  • Cardiovascular Medicine

Background:

  • Calcified cerebral emboli are an under-recognized cause of ischemic stroke.
  • Recent literature suggests their prevalence may be higher than previously thought.
  • Distinguishing these from incidental intracranial calcification is crucial.

Purpose of the Study:

  • To determine the prevalence of calcified cerebral emboli as the primary cause of stroke.
  • To compare cases of calcified cerebral emboli with incidental intracranial calcifications.
  • To analyze the characteristics and outcomes of stroke patients with calcified cerebral emboli.

Main Methods:

  • Review of 220 confirmed stroke cases (May 2014-May 2017) for etiology.
  • Categorization of presumed calcified cerebral emboli as 'possible' or 'definite'.
  • Analysis of morphology, distribution, density, embolic source, interventions, and outcomes.
  • Review of 220 control CT scans for intravascular calcification.

Main Results:

  • Calcified cerebral emboli were the most likely cause in 5.9% (13/220) of stroke cases.
  • Eight cases were definite, with 12 involving anterior circulation.
  • All patients had moderate calcified atherosclerotic disease in aorta/carotid arteries.
  • Three control cases had incidental intravascular calcification.

Conclusions:

  • Calcified cerebral emboli are more commonly associated with spontaneous cerebral infarction than previously believed.
  • Recognition is vital for acute stroke diagnosis, treatment modification, and prognosis.
  • Further research is needed due to limited current literature.