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Effect of Topical Propolis on Wound Healing Process After Tonsillectomy: Randomized Controlled Study
Jeong Hwan Moon1,2, Min Young Lee1,2, Young-Jun Chung1,2
1Department of Otolaryngology-Head and Neck Surgery, Dankook University College of Medicine, Cheonan, Korea.
Clinical and Experimental Otorhinolaryngology
|April 18, 2018
Summary
Propolis extract significantly reduced pain and bleeding after tonsillectomy. This natural remedy also accelerated wound healing in patients, offering a beneficial alternative for post-operative care.
Area of Science:
- Otolaryngology
- Pharmacology
- Natural Products Research
Background:
- Post-tonsillectomy complications include significant pain and hemorrhage.
- Effective management strategies for post-tonsillectomy recovery are crucial.
Purpose of the Study:
- To evaluate the efficacy of water-soluble ethanol extract of propolis in managing post-tonsillectomy pain and hemorrhage.
- To assess the impact of propolis on the healing of tonsillar fossae post-surgery.
Main Methods:
- A randomized controlled trial involving 130 patients undergoing tonsillectomy or adenotonsillectomy.
- Patients were divided into a control group and a propolis group, with the latter receiving propolis orally and as a gargle post-surgery.
- Pain was assessed using a visual analogue scale, and wound healing was evaluated by scoring membrane presence on specific postoperative days. Bleeding incidence was also recorded.
Main Results:
- The propolis group experienced significantly less post-tonsillectomy pain on postoperative days 3 and 7-10 compared to the control group.
- A significant reduction in post-tonsillectomy hemorrhage was observed in the propolis group (P<0.05).
- Wound healing of the tonsillar fossae was significantly improved in the propolis group by postoperative day 7-10 (P=0.002).
Conclusions:
- Propolis application demonstrates a beneficial effect in reducing postoperative pain following tonsillectomy.
- Propolis aids in preventing hemorrhage and accelerating the healing process of tonsillar fossae.
- Water-soluble ethanol extract of propolis is a promising agent for improving outcomes after tonsillectomy.
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