Related Experiment Video
Updated: Feb 11, 2026

Mapping RNA-RNA Interactions Globally Using Biotinylated Psoralen
Published on: May 24, 2017
Defining the global health system and systematically mapping its network of actors
Steven J Hoffman1,2,3, Clarke B Cole4,5
1Global Strategy Lab, Dahdaleh Institute for Global Health Research, Faculty of Health and Osgoode Hall Law School, York University, 4700 Keele Street, Toronto, Ontario, M3J 1P3, Canada. steven.hoffman@globalstrategylab.org.
Background:
The global health system has faced significant expansion over the past few decades, including continued increase in both the number and diversity of actors operating within it. However, without a stronger understanding of what the global health system encompasses, coordination of actors and resources to address today's global health challenges will not be possible.
Methods:
This study presents a conceptually sound and operational definition of the global health system. Importantly, this definition can be applied in practice to facilitate analysis of the system. The study tested the analytical helpfulness of this definition through a network mapping exercise, whereby the interconnected nature of websites representing actors in the global health system was studied.
Results:
Using a systematic methodology and related search functions, 203 global health actors were identified, representing the largest and most transparent list of its kind to date. Identified global health actors were characterized and the structure of their social network revealed intriguing patterns in relationships among actors.
Conclusions:
These findings provide a foundation for future inquiries into the global health system's structure and dynamics that are critical if we are to better coordinate system activities and ensure successful response to our most pressing global health challenges.
Related Concept Videos
Protein Networks
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Actor-Observer Effect
Global Climate Change
Random and Systematic Errors
Systematic Sampling Method
Systematic sampling is one of the simplest methods...
Network Covalent Solids
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...

