Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

8.2K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
8.2K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

3.7K
3.7K
Mechanical Ventilation II: Invasive Ventilation01:23

Mechanical Ventilation II: Invasive Ventilation

788
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
788
Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

616
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
616
Predicting Molecular Geometry02:27

Predicting Molecular Geometry

46.1K
VSEPR Theory for Determination of Electron Pair Geometries
46.1K
Gastric Motility01:16

Gastric Motility

3.3K
Gastric motility is the coordinated contraction and relaxation of stomach muscles that convert ingested food into chyme, a semi-liquid substance ready for further digestion in the intestines. The process begins with the vagus nerve inducing the relaxation of the smooth muscles in the fundus and body of the stomach, allowing these regions to expand and accommodate up to approximately 1.5 liters of food and liquid.
Peristaltic Waves and Chyme Formation
Upon food entry, the stomach initiates...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of tidal volume on gas exchange during rescue ventilation.

Respiratory physiology & neurobiology·2019
Same author

Breath-Hold Diving.

Comprehensive Physiology·2018
Same author

Commentaries on Viewpoint: Why predominantly neurological DCS in breath-hold divers?

Journal of applied physiology (Bethesda, Md. : 1985)·2016
Same author

Lung compression effects on gas exchange in human breath-hold diving.

Respiratory physiology & neurobiology·2009
Same author

Mechanics of airway and alveolar collapse in human breath-hold diving.

Respiratory physiology & neurobiology·2007
Same author

Computer simulation of human breath-hold diving: cardiovascular adjustments.

European journal of applied physiology·2007
Same journal

Response to the Letter to the Editor Regarding "Comparative Evaluation of Risk Scores for Predicting Postoperative Pulmonary Complications".

Respiratory care·2026
Same journal

Respiratory Muscle Dysfunction in Stable COPD: A Multimodal Assessment of Diaphragmatic and Cough-Related Impairment.

Respiratory care·2026
Same journal

Flow Asynchronies During Pressure Support Ventilation in Children: A Bench Model Study.

Respiratory care·2026
Same journal

Inspiratory Effort Assessment Using the Occlusion Pressure-Derived Tension-Time Index.

Respiratory care·2026
Same journal

Clinical Usage of High-Flow Nasal Cannula Across Disease Categories and Care Settings: A Nationwide Cohort Study in Japan.

Respiratory care·2026
Same journal

Efficacy of Mechanical Insufflation-Exsufflation Devices as Analyzed in Lung Models: Systematic Review and Network Meta-Analysis of Peak Expiratory Flow Data.

Respiratory care·2026
See all related articles

Related Experiment Video

Updated: Feb 11, 2026

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation
04:46

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation

Published on: January 17, 2011

22.1K

Fast or Slow Rescue Ventilations: A Predictive Model of Gastric Inflation.

John R Fitz-Clarke1

  • 1Department of Emergency Medicine, Dalhousie University, Halifax, Nova Scotia, Canada. jfitzclarke@eastlink.ca.

Respiratory Care
|April 19, 2018
PubMed
Summary
This summary is machine-generated.

Optimal rescue ventilation involves a 1-second breath duration to minimize gastric inflation and reduce aspiration risk during emergencies. This ensures adequate oxygen delivery while protecting the airway.

Keywords:
basic life supportgastric inflationrescue breathingtidal volumeunprotected airwayventilation

More Related Videos

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
03:05

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Published on: February 16, 2024

1.6K
A Mouse Model of Orotracheal Intubation and Ventilated Lung Ischemia Reperfusion Surgery
09:07

A Mouse Model of Orotracheal Intubation and Ventilated Lung Ischemia Reperfusion Surgery

Published on: September 9, 2022

4.6K

Related Experiment Videos

Last Updated: Feb 11, 2026

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation
04:46

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation

Published on: January 17, 2011

22.1K
Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
03:05

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Published on: February 16, 2024

1.6K
A Mouse Model of Orotracheal Intubation and Ventilated Lung Ischemia Reperfusion Surgery
09:07

A Mouse Model of Orotracheal Intubation and Ventilated Lung Ischemia Reperfusion Surgery

Published on: September 9, 2022

4.6K

Area of Science:

  • Emergency Medicine
  • Physiology
  • Respiratory Care

Background:

  • Rescue ventilation is critical during cardiac and respiratory arrest.
  • Excessive pressure during ventilation can lead to gastric inflation, regurgitation, and aspiration.
  • Optimal techniques aim to minimize gastric inflation while ensuring adequate oxygenation.

Purpose of the Study:

  • To determine the ideal breath duration for rescue ventilation.
  • To compare fast versus slow breath delivery and their impact on gas flow.
  • To model and predict gastric inflation rates and optimal ventilation timing.

Main Methods:

  • A physiological model simulating pulmonary and esophageal pressures was used.
  • Investigated mouth pressure profiles mimicking mouth-to-mouth and bag-valve-mask ventilation.
  • Varied tidal volumes, airway compliance, and resistance to assess their effects.

Main Results:

  • Rapid breaths (<1s) required high pressures, increasing gastric inflation risk.
  • Slow breaths (>1s) lowered pressure but prolonged exposure, also increasing gastric inflation.
  • A breath duration of approximately 1 second minimized gastric inflation in most simulated scenarios.
  • Low esophageal sphincter pressure or high airway resistance altered optimal breath duration.

Conclusions:

  • A 1-second breath duration is theorized as optimal for minimizing gastric inflation during unprotected airway rescue ventilation.
  • This finding offers a unifying explanation for previous study outcomes regarding ventilation strategies.
  • The study provides a theoretical framework for optimizing rescue ventilation techniques.