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Evaluation of the sensitising potential of 4 polyamines present in technical triethylenetetramine using 2 animal
J Maisey1, R Purchase, M C Robbins
1British Industrial Biological Research Association, Carshalton, Surrey, UK.
Contact Dermatitis
|March 1, 1988
Abstract:
Contact sensitivity to 4 polyamines present in technical grade triethylenetetramine was investigated using the 'VAA mouse' assay and the guinea pig maximization test (GPMT). The criteria used to assess sensitivity in the GPMT classed all substances as having the same degree of sensitising potential. The mouse assay ranked N-(2-piperazin-1-ylethyl)ethylenediamine as having a significantly greater sensitising potential than the other compounds.