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Chromium in Postmortem Material
Danuta Dudek-Adamska1, Teresa Lech2, Tomasz Konopka3
1Department of Analytical Chemistry, Faculty of Chemistry of the Jagiellonian University, Gronostajowa 2, 30-387, Kraków, Poland. dudekd@chemia.uj.edu.pl.
Biological Trace Element Research
|April 19, 2018
Summary
This study determined chromium levels in human blood and organs from non-occupationally exposed individuals in Southern Poland. Reference ranges were established for chromium concentration in various tissues, providing crucial baseline data.
Area of Science:
- Environmental Science
- Toxicology
- Human Physiology
Background:
- Growing concern over heavy metal pollution and its impact on human health.
- Need for accurate biomonitoring of environmental contaminants in human tissues.
- Establishment of reference ranges for essential and toxic elements is vital for health assessments.
Purpose of the Study:
- To determine the concentration of chromium in human biological samples.
- To establish reference ranges for chromium in blood and internal organs.
- To provide baseline data for chromium levels in a non-occupationally exposed population.
Main Methods:
- Autopsy samples from 21 females and 39 males were analyzed.
- Microwave-assisted acid digestion was used for sample preparation.
- Electrothermal atomic absorption spectrometry (ETAAS) was employed for elemental analysis.
Main Results:
- Reference ranges for chromium in blood (0.11-16.4 ng/mL) and organs (brain, stomach, liver, kidneys, lungs, heart) were determined.
- Significant variations in chromium concentrations were observed across different tissues.
- Data provides the first reference ranges for chromium in Southern Poland's population.
Conclusions:
- Established reference ranges are essential for interpreting chromium levels in clinical and forensic toxicology.
- This study contributes valuable data for environmental health risk assessment.
- Further research is needed to explore factors influencing chromium accumulation in human tissues.
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