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Updated: Feb 11, 2026

Urethral Stricture Induction Followed by Buccal Mucosa Graft Urethroplasty in a Rat Model
Published on: April 28, 2023
Combined Dorsal and Ventral Onlay Buccal Graft Technique for Large and Complex Penile Strictures
Nikolaos Mertziotis1, Andreas Konandreas1, Christos Kyratsas1
1IASO General Hospital, Athens, Greece.
Purpose:
To present a modified technique of managing extensive penile urethral strictures with dorsal and ventral onlay buccal mucosa grafts.
Patients And Methods:
From October 2014 to January 2016, a total of 12 patients underwent urethroplasty for penile urethral strictures, using dorsal and ventral onlay grafts from buccal mucosa. The mean age was 42.75 (17-71). All patients completed the IPSS and QoL questionnaire, and uroflowmetry was done preoperatively. After surgery, the follow-up included completion of IPSS and QoL questionnaire and measuring of uroflow at 1, 3, 6, and 12 months. Postoperative urethrography was performed in complex cases or in the event of deterioration of voiding symptoms.
Results:
The mean length of the strictures was 5.45 (2, 2-16) cm. Mean Qmax changed from 3.45 ml/sec preoperatively to 18.33 postoperatively, and mean IPS score significantly decreased from 20.1 preoperatively to 8.98 postoperatively. All values were statistically significant (p < 0.001). No intraoperative or immediate postoperative complications were recorded. Overall, at 12 months, 11 out of 12 patients (91.6%) had a marked improvement in quality of life and uroflowmetry parameters.
Conclusions:
In the properly selected patient, the combined use of double graft for penile urethral strictures can be successful with minimal morbidity, at short-term follow-up.
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