Related Experiment Video
Updated: Feb 11, 2026

Evaluation of Right Ventricular Function in Experimental Models of Pulmonary Arterial Hypertension
Published on: June 27, 2025
Effect of abnormal right heart structures on the diagnosis of pulmonary hypertension
Batool AbuHalimeh1, Milind Y Desai2, Adriano R Tonelli1,3
11 2569 Pathobiology Division, Lerner Research Institute, Cleveland Clinic, OH, USA.
Abstract:
The diagnosis of pulmonary hypertension (PH) requires a right heart catheterization (RHC) that reveals a mean pulmonary artery pressure ≥ 25 mmHg. The pulmonary artery catheter traverse the right atrium and ventricle on its way to the pulmonary artery. The presence of abnormal right heart structures, i.e. thrombus, vegetation, benign or malignant cardiac lesions, can lead to complications during this procedure. On the other hand, avoidance of RHC delays the diagnosis and treatment of PH, an approach that might be associated with worse outcomes. This paper discusses the impact of right heart lesions on the diagnosis of PH and suggests an approach on how to manage this association.
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