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Dengue virus not detected in human semen
James S Molton1,2, Isaac Low1, Milly Ming Ju Choy3
1University Medicine Cluster, National University Health System, Singapore.
Journal of Travel Medicine
|April 20, 2018
Summary
Dengue virus does not appear to be sexually transmitted. Testing semen from five dengue patients found no detectable virus, unlike Zika and Ebola.
Area of Science:
- Virology
- Infectious Diseases
- Public Health
Background:
- Zika and Ebola viruses are known to persist in semen.
- Sexual transmission is a documented route for Zika and Ebola virus spread.
- Flaviruses share biological characteristics, necessitating investigation into other members like dengue virus.
Purpose of the Study:
- To investigate the potential for sexual transmission of dengue virus.
- To determine if dengue virus is detectable in semen of infected individuals.
Main Methods:
- Semen samples were collected from five patients during acute dengue virus infection.
- Dengue virus-specific PCR assays were performed on all semen samples.
Main Results:
- All five semen samples tested negative for dengue virus.
- No detectable levels of dengue virus were found in the semen of acutely infected patients.
Conclusions:
- Dengue virus is unlikely to be transmitted sexually.
- The risk of sexual transmission for dengue virus appears to be negligible.
- Further research may be warranted to confirm these findings in a larger cohort.
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