Related Experiment Video
Updated: Feb 11, 2026

Uncontrolled Hemorrhagic Shock Modeled via Liver Laceration in Mice with Real Time Hemodynamic Monitoring
Published on: May 21, 2017
A new surgical strategy for medically uncontrolled protein-losing enteropathy after Fontan surgery
Seul Gi Cha1, Gi Beom Kim1, Chung Il Noh1
1Department of Pediatrics, Seoul National University Children's Hospital, Seoul, South Korea.
Insights
Managing protein-losing enteropathy after Fontan surgery is difficult. Surgical intervention involving Fontan takedown and pulsatile bidirectional cavopulmonary shunting successfully treated a pediatric patient unresponsive to medical management.
Area of Science:
- Cardiology
- Pediatric Gastroenterology
- Surgical Innovation
Background:
- Protein-losing enteropathy (PLE) is a challenging complication following Fontan surgery.
- Managing PLE in patients with Fontan circulation requires innovative therapeutic strategies.
Observation:
- A 14-year-old boy with Fontan circulation developed protein-losing enteropathy.
- The patient underwent two years of medical treatment without significant clinical improvement.
Findings:
- Surgical intervention, including Fontan takedown and conversion to pulsatile bidirectional cavopulmonary shunting, resolved the protein-losing enteropathy.
- This case highlights the potential efficacy of surgical revision in refractory PLE post-Fontan.
Implications:
- Fontan takedown and conversion to pulsatile flow may be a viable treatment option for intractable protein-losing enteropathy.
- This approach could improve outcomes for Fontan patients experiencing severe gastrointestinal complications.
Abstract:
Managing protein-losing enteropathy after Fontan surgery is challenging. We report a case of protein-losing enteropathy associated with Fontan circulation in a 14-year-old boy. He was treated medically for 2 years, without improvement until Fontan takedown and pulsatile bidirectional cavopulmonary shunting were performed.
More Related Videos
11:40Preparation of the Mgm101 Recombination Protein by MBP-based Tagging Strategy
Published on: June 25, 2013
11:46Investigation of the Electrophysiological and Thermographic Safety Parameters of Surgical Energy Devices During Thyroid and Parathyroid Surgery in a Porcine Model
Published on: October 13, 2022
Related Concept Videos
Inhaled Medications
Covalently Linked Protein Regulators
These groups modify specific amino acids in a protein....
Endocarditis III: Medical Management
Myocarditis III: Medical Management
Pericarditis III: Medical Management
Heart Failure V: Medical Management