Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Emission Spectra02:39

Emission Spectra

76.5K
When solids, liquids, or condensed gases are heated sufficiently, they radiate some of the excess energy as light. Photons produced in this manner have a range of energies, and thereby produce a continuous spectrum in which an unbroken series of wavelengths is present.
76.5K
Accelerators01:17

Accelerators

292
Accelerators in concrete serve as admixtures to speed up the hardening process, enabling the concrete to achieve early strength faster. Although accelerators do not necessarily impact the time it takes concrete to set, they reduce this time in practice. A common accelerator is calcium chloride, which is particularly useful for hastening early strength development in cold weather or for rapid repair jobs that require quick heat generation after mixing.
The effectiveness of calcium chloride can...
292
Linear Equations01:27

Linear Equations

501
Linear equations form the foundation of many algebraic and real-world applications, characterized by their simplicity and utility. A linear equation is an algebraic statement in which each term is either a constant or a product of a constant and a single variable. These equations represent straight lines when plotted on a Cartesian coordinate plane, reflecting a constant rate of change between two quantities.A typical linear equation in one variable has the form: ax + b = c, where a, b, and c...
501
Linear Circuits01:17

Linear Circuits

887
A linear circuit is characterized by its output having a direct proportionality to its input, adhering to the linearity property, which encompasses the principles of homogeneity (scaling) and additivity. Homogeneity dictates that when the input, also referred to as the excitation, is multiplied by a constant factor, the output, known as the response, is correspondingly scaled by the same constant factor. For instance, if the current is multiplied by a constant 'k,' the voltage likewise...
887
Inhaled Medications01:23

Inhaled Medications

829
Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
829
Average Acceleration01:30

Average Acceleration

14.4K
The importance of understanding acceleration spans our day-to-day experiences, as well as the vast reaches of outer space and the tiny world of subatomic physics. In everyday conversation, to accelerate means to speed up. For instance, we are familiar with the acceleration of our car; the harder we apply our foot to the gas pedal, the faster we accelerate. The greater the acceleration, the greater the change in velocity over a given time. Acceleration is widely seen in experimental physics. In...
14.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Defining the Hospital Night: Deriving and Validating Electronic Health Record-Based Measures of the Inpatient Sleep Experience.

Sleep·2026
Same author

Knowledge-based deep residual U-Net (DRU) for synthetic CT generation using a single MR volume for frameless radiosurgery.

Journal of applied clinical medical physics·2025
Same author

Investigating the FLASH Effect in a Rat Brain Organotypic Model With a Novel High-Energy Electron Beam.

International journal of radiation oncology, biology, physics·2025
Same author

Investigating Rat-Brain Normal Tissue and Tumor FLASH Effects with a Novel Very High Energy Electron Beam.

bioRxiv : the preprint server for biology·2025
Same author

Benchmarking of a new integrated 3D dosimetry system against Monte Carlo calculations and an established optical CT scanner.

Medical physics·2025
Same author

Uncertainty quantification in multi-parametric MRI-based meningioma radiotherapy target segmentation.

Frontiers in oncology·2025
Same journal

Correction to "On the shape of the radiation survival curve in tumor spheroids: The role of oxygen heterogeneity".

Medical physics·2026
Same journal

Multi-view constrained semi-supervised vertebra detection for 3D ultrasound spine volume.

Medical physics·2026
Same journal

Accuracy of quantitative <sup>177</sup>Lu SPECT/CT imaging: A systematic review.

Medical physics·2026
Same journal

Physics-constrained dual-domain network for CBCT reconstruction from orthogonal X-rays in gynecologic radiotherapy.

Medical physics·2026
Same journal

Decomposition-based harmonization for quantitative PET imaging across scanners and radiotracers.

Medical physics·2026
Same journal

Development and evaluation of an in vivo dose-based monitoring system for electron FLASH radiation therapy.

Medical physics·2026
See all related articles

Related Experiment Video

Updated: Feb 11, 2026

Use of a Linear Accelerator for Conducting In Vitro Radiobiology Experiments
06:08

Use of a Linear Accelerator for Conducting In Vitro Radiobiology Experiments

Published on: May 26, 2019

8.0K

Technical Note: On maximizing Cherenkov emissions from medical linear accelerators.

Zachary Shrock1, Suk W Yoon1, Rathnayaka Gunasingha2

  • 1Medical Physics Graduate Program, Duke University, Durham, North Carolina, 27708, USA.

Medical Physics
|April 20, 2018
PubMed
Summary
This summary is machine-generated.

Increasing photon energy and using specialized filters significantly boosts Cherenkov light production in megavoltage (MV) radiotherapy. This enhancement is crucial for improving Cherenkov imaging and therapeutic applications.

Keywords:
GAMOSRDTRECACherenkovPsoralen

More Related Videos

Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
05:54

Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

18.2K
Technical Detail for Robot Assisted Pancreaticoduodenectomy
14:45

Technical Detail for Robot Assisted Pancreaticoduodenectomy

Published on: September 28, 2019

15.6K

Related Experiment Videos

Last Updated: Feb 11, 2026

Use of a Linear Accelerator for Conducting In Vitro Radiobiology Experiments
06:08

Use of a Linear Accelerator for Conducting In Vitro Radiobiology Experiments

Published on: May 26, 2019

8.0K
Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
05:54

Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

18.2K
Technical Detail for Robot Assisted Pancreaticoduodenectomy
14:45

Technical Detail for Robot Assisted Pancreaticoduodenectomy

Published on: September 28, 2019

15.6K

Area of Science:

  • Medical Physics
  • Radiotherapy
  • Cherenkov Radiation

Background:

  • Cherenkov light in megavoltage (MV) radiotherapy offers imaging and therapeutic potential.
  • Low Cherenkov light fluence currently limits its clinical applications.

Purpose of the Study:

  • To investigate methods for increasing Cherenkov light production during MV radiotherapy.
  • To evaluate the impact of increased photon energy and beam-hardening filtration.

Main Methods:

  • Monte Carlo simulations using GAMOS 5.0.0 modeled clinical linear accelerator photon beams.
  • Simulations used a water phantom and varied photon energies and filter materials (aluminum, iron, copper).
  • Cherenkov production and dose were analyzed at different depths, with dose rates considered.

Main Results:

  • Higher photon beam energy significantly increases Cherenkov production per dose; 18 MV beams produced 3.3-4.0x more photons than 6 MV.
  • Aluminum filtration enhanced Cherenkov production by 1.6-1.7x in a 10 MV beam while maintaining clinical dose rates.
  • Specialized filtration, particularly with aluminum, proved more effective than standard flattening filters.

Conclusions:

  • Combining increased photon energy and specialized beam-hardening filtration substantially enhances Cherenkov photon yield per radiotherapy dose.
  • These findings support the development of improved Cherenkov-based imaging and therapeutic techniques in MV radiotherapy.