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Updated: Feb 11, 2026

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
Published on: November 29, 2024
NMR-based metabolomics of biofluids in cancer
Guro F Giskeødegård1, Torfinn S Madssen1, Leslie R Euceda1
1Department of Circulation and Medical Imaging, Norwegian University of Science and Technology-NTNU, Trondheim, Norway.
Abstract:
This review describes the current status of NMR-based metabolomics of biofluids with respect to cancer risk assessment, detection, disease characterization, prognosis, and treatment monitoring. While the metabolism of cancer cells is altered compared with that of non-proliferating cells, the metabolome of blood and urine reflects the entire organism. We conclude that many studies show impressive associations between biofluid metabolomics and cancer progression, but translation to clinical practice is currently hindered by lack of validation, difficulties in biological interpretation, and non-standardized analytical procedures.
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