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Related Concept Videos

Common Ion Effect03:24

Common Ion Effect

47.0K
Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Châtelier’s principle. Consider the dissolution of silver iodide:
47.0K
Precipitation of Ions03:11

Precipitation of Ions

30.3K
Predicting Precipitation
The equation that describes the equilibrium between solid calcium carbonate and its solvated ions is:
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Ion Channels01:19

Ion Channels

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The movement of ions like sodium, potassium, and calcium into and out of the cell is essential to maintain the electrochemical gradient in living cells. The ion channels—a class of membrane transport proteins—help maintain this ionic gradient for the smooth functioning of physiological activities such as maintaining cell size and volume, conducting nerve impulses, and gas and nutrient exchange.
Ion channels are specialized integral membrane proteins on the plasma membrane that allow...
91.5K
Formation of Complex Ions03:45

Formation of Complex Ions

26.2K
A type of Lewis acid-base chemistry involves the formation of a complex ion (or a coordination complex) comprising a central atom, typically a transition metal cation, surrounded by ions or molecules called ligands. These ligands can be neutral molecules like H2O or NH3, or ions such as CN− or OH−. Often, the ligands act as Lewis bases, donating a pair of electrons to the central atom. These types of Lewis acid-base reactions are examples of a broad subdiscipline called coordination...
26.2K
Ions and Ionic Charges03:27

Ions and Ionic Charges

79.4K
In ordinary chemical reactions, the nucleus — which contains the protons and neutrons of each atom and thus identifies the element — remains unchanged. Electrons, however, can be added to atoms by transfer from other atoms, lost by transfer to other atoms, or shared with other atoms. The transfer and sharing of electrons among atoms govern the chemistry of the elements. During the formation of some compounds, atoms gain or lose electrons to form electrically charged particles called...
79.4K
Ions as Acids and Bases02:54

Ions as Acids and Bases

26.6K
Salts with Acidic Ions
Salts are ionic compounds composed of cations and anions, either of which may be capable of undergoing an acid or base ionization reaction with water. Aqueous salt solutions, therefore, may be acidic, basic, or neutral, depending on the relative acid-base strengths of the salt’s constituent ions. For example, dissolving the ammonium chloride in water results in its dissociation, as described by the equation:
26.6K

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Updated: Feb 11, 2026

Swab Sampling Method for the Detection of Human Norovirus on Surfaces
10:03

Swab Sampling Method for the Detection of Human Norovirus on Surfaces

Published on: February 6, 2017

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Direct ion generation from swabs.

Alan K Jarmusch1, Valentina Pirro1, David L Logsdon1

  • 1Department of Chemistry and Center for Analytical Instrumentation Development, Purdue University, West Lafayette, IN 47907, United States.

Talanta
|April 21, 2018
PubMed
Summary
This summary is machine-generated.

Medical swabs can now be used as electrospray ionization probes for direct mass spectrometry. This novel technique allows for versatile biofluid and tissue analysis in various clinical applications.

Keywords:
Ambient ionizationElectrosprayIn vivo samplingMass spectrometryMedical swabsPoint-of-care testing

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Area of Science:

  • Analytical Chemistry
  • Biomedical Engineering
  • Mass Spectrometry

Background:

  • Medical swabs are standard tools for collecting biological samples.
  • Direct analysis of biofluids and tissues is crucial for clinical diagnostics.

Purpose of the Study:

  • To introduce and evaluate medical swabs as electrospray ionization probes.
  • To explore the potential of this novel approach for direct mass spectrometry.

Main Methods:

  • Investigating ion generation from medical swabs.
  • Characterizing the ionization behavior using microscopic videography.
  • Demonstrating applications through illustrative examples.

Main Results:

  • Successful ion generation using medical swabs as probes.
  • Detailed characterization of the electrospray ionization process.
  • Presentation of diverse application scenarios.

Conclusions:

  • Medical swabs offer a novel and adaptable platform for electrospray ionization.
  • This method enables direct mass spectrometric analysis of biological samples.
  • The technique holds significant potential for widespread clinical applications.