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Comparison of 3T Intracranial Vessel Wall MRI Sequences

A Lindenholz1, A A Harteveld2, J J M Zwanenburg2

  • 1From the Department of Radiology (A.L., A.A.H., J.J.M.Z., J.C.W.S., J.H.) University Medical Center Utrecht, Utrecht, the Netherlands A.Lindenholz@umcutrecht.nl.

AJNR. American Journal of Neuroradiology
|April 21, 2018
PubMed
Abstract

Insights

A faster intracranial vessel wall MRI sequence (4:39 minutes) maintains high image quality and detects all lesions. This 30% speed improvement offers better diagnostic efficiency for intracranial vascular diseases.

Area of Science:

  • Radiology
  • Medical Imaging
  • Neuroimaging

Background:

  • Intracranial vessel wall MR imaging is crucial for diagnosing vascular diseases.
  • Current imaging protocols require long scan times due to multiple sequences (pre- and postcontrast).
  • Reducing scan duration is essential for clinical efficiency.

Purpose of the Study:

  • To evaluate intracranial vessel wall sequence variants for reduced scan duration.
  • To maintain acceptable image quality while shortening scan times.

Main Methods:

  • Seven intracranial vessel wall sequence variants were tested, with scan times ranging from 4:39 to 8:24 minutes.
  • 15 subjects underwent MRI on a 3T scanner, with variants performed precontrast and/or postcontrast.
  • Comparison focused on spatial resolution, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR).

Main Results:

  • The fastest variant (4:39 minutes) demonstrated higher or comparable SNRs/CNRs compared to the reference sequence (6:42 minutes).
  • Qualitative assessment indicated good visibility of intracranial vessel walls with the faster sequence.
  • The 4:39-minute variant successfully identified all vessel wall lesions detected by the longer sequence.

Conclusions:

  • A 30% faster vessel wall sequence was developed, offering high SNRs/CNRs.
  • This optimized sequence provides good visibility of the intracranial vessel wall.
  • The reduced scan time improves diagnostic potential without compromising image quality.

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