Related Experiment Video
Updated: Feb 11, 2026

Assessment of Thermal Damage from Robot-Drilled Craniotomy for Cranial Window Surgery in Mice
Published on: November 11, 2022
Earliest Animal Cranial Surgery: from Cow to Man in the Neolithic
Fernando Ramirez Rozzi1, Alain Froment2
1AMIS UMR 5288 CNRS. Faculté de Chirurgie Dentaire, 1 rue Maurice Arnoux, 92120, Montrouge, France. fernando.ramirez-rozzi@cnrs.fr.
Neolithic humans performed cranial surgery on cows, demonstrating advanced bone surgical skills. This earliest evidence of animal surgery may indicate veterinary practice or technique refinement before human application.
Area of Science:
- Archaeology
- Paleopathology
- Veterinary History
Background:
- Cranial surgery, or trepanation, has ancient origins dating back to the Mesolithic period.
- Prehistoric humans, including those from the Neolithic period, possessed significant skill in bone surgical techniques.
Observation:
- Analysis of a Neolithic cow cranium (3400-3000 BC) from Champ-Durand, France, revealed a hole in the frontal bone.
- The surgical techniques used on the cow cranium were identical to those employed on human crania during the same period.
Findings:
- The cow cranium shows evidence of cranial surgery, suggesting a potential early form of veterinary surgical practice.
- The practice may have served to treat the animal or as a method for Neolithic people to hone surgical skills on animals before operating on humans.
Implications:
- This discovery could represent the earliest known instance of veterinary surgical intervention.
- It offers insights into the learning and application processes of complex surgical techniques in prehistoric societies.
- The findings challenge our understanding of the development of surgical practices and human-animal interactions in the Neolithic era.
Related Concept Videos
Cranial and Spinal Meninges
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
Cranial Nerves: Types Part I
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
Cranial Nerves: Types Part II
Facial Nerve (Cranial Nerve VII)
Cranial nerve VII, or the facial nerve,...
Cranial Part of Parasympathetic Division
The vagus nerve (cranial nerve X) alone accounts for approximately 75...
Cranial Nerves: Overview and Anatomy
Tonicity in Animals

