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Helicobacter cinaedi-associated Carotid Arteritis
Shinichiro Nakao1, Hideharu Hagiya, Keigo Kimura
1Department of General Internal Medicine, Osaka University Hospital, Suita, Osaka 565-0871, Japan.chin9501@gmail.com.
Insights
Helicobacter cinaedi infection was diagnosed in a patient with carotid atherosclerosis, leading to carotid arteritis and a transient ischemic attack. Antibiotic treatment was effective in resolving the infection and associated symptoms.
Area of Science:
- Infectious Diseases
- Cardiovascular Medicine
- Vascular Surgery
Background:
- Carotid atherosclerosis is a significant risk factor for cerebrovascular events.
- Infectious agents are increasingly recognized as potential contributors to vascular inflammation and atherosclerosis.
- Helicobacter cinaedi, a rare pathogen, has not been extensively linked to carotid artery disease.
Abstract:
A 65-year-old Japanese man with bilateral carotid atherosclerosis presented with right neck pain and fever. Contrast-enhanced computed tomography suggested carotid arteritis, and carotid ultrasonography showed an unstable plaque. The patient developed a cerebral embolism, causing a transient ischemic attack. Helicobacter cinaedi was detected in blood culture, and H. cinaedi-associated carotid arteritis was diagnosed. Empirical antibiotic therapy was administered for 6 weeks. After readmission for recurrent fever, he was treated another 8 weeks. Although the relationship between H. cinaedi infection and atherosclerosis development remains unclear, the atherosclerotic changes in our patient's carotid artery might have been attributable to H. cinaedi infection.
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