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Related Experiment Video

Updated: Feb 11, 2026

Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation
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Postoperative intraocular lens opacification.

Shang-Te Ma1, Chung-May Yang1, Yu-Chih Hou1,2

  • 1Department of Ophthalmology, National Taiwan University Hospital, University College of Medicine, Taipei, Taiwan.

Taiwan Journal of Ophthalmology
|April 21, 2018
PubMed
Summary
This summary is machine-generated.

Intraocular lens (IOL) opacification is a rare complication that can occur after specific eye surgeries like n-DSAEK and PPV. This phenomenon may be linked to air injections or underlying health conditions.

Keywords:
Intraocular air injectionintraocular lensnon-Descemet stripping automated endothelial keratoplastyopacification

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Area of Science:

  • Ophthalmology
  • Medical Devices
  • Surgical Complications

Background:

  • Intraocular lens (IOL) opacification is an uncommon complication.
  • It can occur after procedures such as non-Descemet stripping automated endothelial keratoplasty (n-DSAEK) and pars plana vitrectomy (PPV).
  • Understanding the factors contributing to IOL opacification is crucial for patient outcomes.

Observation:

  • Two cases of pupillary IOL opacification were reported following n-DSAEK and PPV with intravitreal air injection.
  • Anterior segment optical coherence tomography (AS-OCT) revealed hyperreflective materials on the anterior IOL surface in both instances.
  • Patients experienced a decrease in visual acuity, though it remained stable over follow-up periods.

Findings:

  • IOL opacification presented as fine granular deposits on the anterior IOL surface.
  • The condition was observed in a hydrophobic acrylic IOL after PPV and air injection.
  • The opacification was associated with prior n-DSAEK and intravitreal air injection, respectively.

Implications:

  • This suggests that intraocular air injection and systemic diseases may be predisposing factors for IOL opacification.
  • Further research is needed to elucidate the exact mechanisms and long-term effects.
  • Awareness of this complication is important for ophthalmic surgeons performing n-DSAEK and PPV.