Related Experiment Video
Updated: Feb 11, 2026

Corneal Tissue Engineering: An In Vitro Model of the Stromal-nerve Interactions of the Human Cornea
Published on: January 24, 2018
Corneal fibroma: An uncommon stromal tumor
Akshay Gopinathan Nair1, Hemal Kenia2, Indumati Gopinathan3
1Mehta Eye Clinic, Ghatkopar, Mumbai; Ophthalmic Plastic Surgery & Ocular Oncology Services, Advanced Eye Hospital & Institute, Navi Mumbai, India.
Abstract:
A 56-year-old male patient presented with a slow-growing, elevated, smooth, white corneal mass. The mass was excised by performing an alcohol-assisted keratoepitheliectomy and sent for histopathological examination. Subepithelially, closely packed spindle cells in "feather-stitched" or storiform pattern were seen. Immunohistochemically, the cells stained negatively for CD-34 and S-100 and focal positivity was seen for vimentin. Based on the morphology and immunochemical staining, a diagnosis of corneal fibroma was made. No recurrence was seen. Corneal fibroma is an exceedingly rare, benign tumor and possibly lies on the same spectrum as corneal keloid and hypertrophic cicatrix. Surgical resection is usually curative.
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