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A resistor is an ohmic device that limits the flow of charge in a circuit. Most circuits have more than one resistor. If several resistors are connected together and connected to a battery, the current supplied by the battery depends on the equivalent resistance of the circuit. The equivalent resistance of a combination of resistors depends on both their individual values and how they are connected. The simplest combination of resistors is the series combination. 
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A Surgical Approach for Optic Nerve Crush in a Rabbit Model
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Optic nerve aplasia: A case series.

K Samyukta Sadasivan1, Neelam Pawar1, Meenakshi Ravindran1

  • 1Department of Paediatric Ophthalmology and Squint, Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India.

Indian Journal of Ophthalmology
|April 21, 2018
PubMed
Summary
This summary is machine-generated.

Optic nerve aplasia (ONA) is a rare congenital condition where the optic nerve is absent. This summary details varied clinical presentations of ONA in three patients.

Keywords:
Aplasia of optic nervecentral nervous system anomalycongenital optic nerve anomaly

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Area of Science:

  • Ophthalmology
  • Medical Genetics
  • Developmental Biology

Background:

  • Optic nerve aplasia (ONA) is a congenital anomaly defined by the absence of the optic nerve head, retinal vasculature, ganglion cells, and nerve fibers.
  • ONA can present as a unilateral or bilateral condition, often associated with systemic or ocular abnormalities.

Observation:

  • This report details three cases of optic nerve aplasia with diverse clinical manifestations.
  • Clinical findings include absence of light perception, afferent pupillary defect, and characteristic fundus appearance.

Findings:

  • Unilateral ONA was observed in an otherwise healthy individual, highlighting the variability in presentation.
  • Bilateral ONA cases are typically associated with systemic anomalies, underscoring the importance of comprehensive evaluation.

Implications:

  • Understanding the varied clinical spectrum of ONA is crucial for accurate diagnosis and management.
  • Further research into the genetic and developmental factors underlying ONA can inform future diagnostic and therapeutic strategies.