Related Experiment Video
Updated: Feb 11, 2026
12:33
Origami Inspired Self-assembly of Patterned and Reconfigurable Particles
Published on: February 4, 2013
22.2K
Core networks and their reconfiguration patterns across cognitive loads.
Nianming Zuo1,2,3, Zhengyi Yang1,2, Yong Liu1,2,4,3
1Brainnetome Center, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China.
Human Brain Mapping
|April 21, 2018
Summary
The frontoparietal network (FPN) and default mode network (DMN) show distinct patterns during working memory (WM) tasks. Intensive brain network reconfiguration across cognitive loads indicates poorer WM performance.
Area of Science:
- Neuroscience
- Cognitive Neuroscience
- Brain Imaging
Background:
- Cognitively demanding tasks engage distributed brain networks.
- Understanding core network configuration and reconfiguration across cognitive loads is crucial.
- The relationship between network dynamics and cognitive task performance needs further clarification.
Purpose of the Study:
- To investigate the configuration and reconfiguration patterns of core brain networks during varying cognitive loads.
- To determine if these network reconfiguration patterns predict cognitive task performance, specifically working memory capacity.
- To differentiate the roles and dynamic changes of the frontoparietal network (FPN) and default mode network (DMN) across cognitive demands.
Main Methods:
- Analysis of functional magnetic resonance imaging (fMRI) data from 448 subjects.
- Examination of brain activity during resting state and N-back working memory (WM) tasks with varying cognitive loads (0-back and 2-back).
- Discrimination of core brain networks based on functional interaction strength and connection flexibility.
Main Results:
- The frontoparietal network (FPN) and default mode network (DMN) were identified as core networks.
- Both FPN and DMN showed strengthened internal connections at low cognitive load (0-back) compared to rest.
- Increased network reconfiguration across cognitive loads correlated with poorer working memory performance.
Conclusions:
- The FPN and DMN exhibit distinct roles and reconfiguration patterns under cognitive load.
- Dynamic changes in brain network configuration are linked to cognitive performance.
- Brain network reconfiguration patterns offer a potential biomarker for evaluating and predicting cognitive capabilities, such as working memory performance.
More Related Videos
04:41Utilizing a Reconfigurable Maze System to Enhance the Reproducibility of Spatial Navigation Tests in Rodents
Published on: December 2, 2022
3.3K
08:42Assessment of Social Cognition in Non-human Primates Using a Network of Computerized Automated Learning Device ALDM Test Systems
Published on: May 5, 2015
12.6K
Related Concept Videos
02:10The Nucleosome Core Particle
14.6K
Nucleosomes are the DNA-histone complex, where the DNA strand is wound around the histone core. The histone core is an octamer containing two copies of H2A, H2B, H3, and H4 histone proteins.
The paradox
Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their main responsibility is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. While on the other hand, they must allow polymerase enzymes to access DNA...
The paradox
Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their main responsibility is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. While on the other hand, they must allow polymerase enzymes to access DNA...
14.6K
01:12The Nucleosome Core Particle
2.4K
Nucleosomes are the DNA-histone complex, where the DNA strand is wound around the histone core. The histone core is an octamer containing two copies of H2A, H2B, H3, and H4 histone proteins.
Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their primary aim is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. On the other hand, they must allow polymerase enzymes to access histone-bound DNA during...
Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their primary aim is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. On the other hand, they must allow polymerase enzymes to access histone-bound DNA during...
2.4K
02:26Protein Networks
4.6K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.6K
01:38Cognitive Dissonance
37.5K
Social psychologists have documented that feeling good about ourselves and maintaining positive self-esteem is a powerful motivator of human behavior (Tavris & Aronson, 2008). In the United States, members of the predominant culture typically think very highly of themselves and view themselves as good people who are above average on many desirable traits (Ehrlinger, Gilovich, & Ross, 2005). Often, our behavior, attitudes, and beliefs are affected when we experience a threat to our...
37.5K
02:18Network Covalent Solids
16.2K
Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
16.2K
01:06Fixed Action Patterns
17.7K
A fixed action pattern (FAP) is a specific, hard-wired sequence of behaviors that occurs in response to an external stimulus, called a sign stimulus. The behavior is “fixed” because it is essentially unchangeable—proceeding similarly across individuals of a species every time it occurs.
17.7K