Related Experiment Video
Updated: Feb 11, 2026

Preparation of SNS CobaltII Pincer Model Complexes of Liver Alcohol Dehydrogenase
Published on: March 19, 2020
The Influence of β-diiminato Ligands on As4 Activation by Cobalt Complexes
Fabian Spitzer1, Gábor Balázs1, Christian Graßl1
1Institut für Anorganische Chemie, Universität Regensburg, Universitätsstrasse 31, 93040, Regensburg, Germany.
Abstract:
In a systematic study of the activation of As4 , three [LCo(tol)] (L=β-diiminato) complexes have revealed different steric and electronic influences. 2,6-Diisopropylphenyl (Dipp) and 2,6-dimethylphenyl (dmp) flanking groups were used, one of the ligands with H backbone substituents (β-dialdiminate L0 ) and two with Me substituents (β-diketiminates L3 and L1 ). In the reaction with As4 , different dinuclear products [(LCo)2 As4 ] (LM=L0 (1), L1 (2), L3 (3)) were isolated, with all showing differently shaped [Co2 As4 ] cores in the solid state: octahedral in 1, prismatic in 2, and asterane-like in 3. Thermal treatment of 3 leads to the abstraction of one arsenic atom to yield [(L3 Co)2 As3 ] (4). All products were comprehensively characterized by single-crystal X-ray diffraction, FD-MS, and 1 H NMR spectroscopy. A rational explanation for the different reactivity is also proposed and DFT calculations shed light on the nature of the highly flexible [Co2 As4 ] cores.
More Related Videos
11:07Biochemical Reconstitution of Steroid Receptor•Hsp90 Protein Complexes and Reactivation of Ligand Binding
Published on: September 21, 2011
07:20Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Related Concept Videos
Metal-Ligand Bonds
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
Complexation Equilibria: Factors Influencing Stability of Complexes
Formation of Complex Ions
Ligand Binding and Linkage
Ligand Binding and Linkage
Ligand Binding Sites
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...