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Author Spotlight: Optimizing Growth Factors for Production of Biotechnologically Relevant Secondary Metabolites
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High-value bioproducts from microalgae: Strategies and progress.

Ming-Hua Liang1, Ling Wang2, Qiming Wang3

  • 1a College of Food Science and Engineering, South China University of Technology , Guangzhou , China.

Critical Reviews in Food Science and Nutrition
|April 21, 2018
PubMed
Summary

Microalgae are sustainable sources for valuable bioproducts like lipids, PUFAs, and carotenoids. This review details strategies, including cultivation and molecular methods, to enhance their production.

Keywords:
LC-PUFAMicroalgaeabiotic stresscarotenoidgene knockouthigh-value bioproductslipidmetabolic engineeringomics

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Area of Science:

  • Biotechnology
  • Phycology
  • Sustainable Resources

Background:

  • Microalgae offer sustainable production of high-value bioproducts like lipids, polyunsaturated fatty acids (PUFAs), and carotenoids.
  • Their high photosynthetic efficiency and lack of arable land requirement make them attractive resources.
  • Enhancing the content and productivity of these specific bioproducts is a critical challenge.

Purpose of the Study:

  • To review high-value bioproducts derived from microalgae.
  • To elucidate the biosynthetic pathways for key compounds (lipids, PUFAs, carotenoids).
  • To summarize recent advancements and strategies for boosting microalgal bioproduct yield.

Main Methods:

  • Optimized cultivation conditions involving abiotic and chemical stresses.
  • Application of metabolic precursors, phytohormones, and oxidative stress inducers.
  • Molecular approaches including metabolic engineering, transcriptional engineering, and gene disruption (RNAi, CRISPR/Cas9).

Main Results:

  • Detailed description of microalgal bioproducts and their synthesis pathways.
  • Overview of strategies to improve yields of lipids, PUFAs, and carotenoids.
  • Highlighting the effectiveness of combined cultivation and molecular techniques.

Conclusions:

  • Microalgae are a significant source for sustainable bioproducts.
  • Various cultivation and molecular strategies can effectively enhance bioproduct accumulation.
  • Further research in optimizing these strategies is crucial for industrial applications.