EAST Multicenter Trial on targeted temperature management for hanging-induced cardiac arrest

Cindy H Hsu1, Bryce E Haac, Mack Drake

  • 1From the R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland (C.H.H., B.E.H., T.M.S., D.M.S.); University of Michigan Ann Arbor, Michigan (C.H.H., I.N.C.); University of Kentucky, Lexington, Kentucky (M.D., A.C.B.); Los Angeles County/University of Southern California Medical Center, Los Angeles, California (A.A., K.I.); Oregon Health & Science University, Portland, Oregon (H.E.H., C.E.); University of California Davis Medical Center, Davis, California (J.G., E.M.T.); University of Washington/Harborview Medical Center, Seattle, Washington (N.J.J., D.C.); Vanderbilt University Medical Center, Nashville, Tennessee (M.F.M., M.B.P.); Loma Linda University Medical Center, Loma Linda, California (K.R.O., C.C.); WakeMed Health & Hospitals, Raleigh, North Carolina (P.O.U., M.F.); Geisinger Medical Center, Danville, Pennsylvania (J.L.W., K.A.Y.); Marshfield Clinic, Marshfield, Wisconsin (D.C.C., D.J.G.); University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (A.W., C.C.); University of Colorado Hospital, Aurora, Colorado (S.M.P., M.G.); Brigham Women's Hospital, Boston, Massachusetts (I.P.A., R.R.S.); San Francisco General Hospital/University of California San Francisco, San Francisco, California (D.Y.M., B.D.); Harbor UCLA Medical Center, Torrance, California (D.Y.K., L.S.).

Summary

Suicidal hanging patients with cardiac arrest (CA) have worse outcomes. Targeted temperature management (TTM) in CA patients showed worse unadjusted survival, but subgroup analysis revealed no significant difference.

Related Concept Videos

Cardiac Catheterization IV: Nursing Management01:26

Cardiac Catheterization IV: Nursing Management

Nursing responsibilities before cardiac catheterization include:Assess for allergies and establish baseline health status.Before cardiac catheterization, assess the patient for allergies to contrast dye. Perform a comprehensive baseline assessment, including vital signs, heart and breath sounds, and a neurovascular assessment of the extremities, noting distal pulses, skin color, and temperature. Instruct the patient to fast for 8-12 hours before the procedure. Evaluate baseline laboratory...
781
Trial and Error and Algorithm01:12

Trial and Error and Algorithm

A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
429
Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
5.0K
Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
10.9K
Body Temperature01:25

Body Temperature

The body's temperature, measured in degrees, is determined by the balance between heat production and dissipation to the surrounding environment. For instance, if exercising vigorously, the body will produce more heat, causing sweat and dissipating that heat. Despite extreme environmental conditions and physical exertion, the human temperature-control system maintains a constant core body temperature (the temperature of deep tissues, which are the tissues located beneath the skin and other...
4.9K
Body Temperature01:07

Body Temperature

Body temperature reflects the equilibrium between heat production and heat loss within the body. Most heat is generated by metabolically active tissues, particularly the liver, heart, brain, kidneys, and endocrine organs. At rest, skeletal muscles contribute 20–30% of total heat production, but during vigorous exercise, this can increase up to 30–40 times.
The average body temperature is approximately 37°C (98.6°F) and typically ranges from 36.1–37.2°C...
1.5K