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Association between hypertension and metabolic disorders among elderly patients in North Jordan

Nuha Alwardat1, Laura Di Renzo2, Renata Costa de Miranda3

  • 1Division of Clinical Nutrition and Nutrigenomics, Department of Biomedicine and prevention, University of Rome "Tor Vergata", Rome, Italy; PhD School of Applied Medical-Surgical Sciences, Faculty of Medicine and Surgery, University of Rome "Tor Vergata", Rome, Italy.

Diabetes & Metabolic Syndrome
|April 22, 2018
PubMed

Insights

Hypertension, dyslipidemia, and hyperglycemia are key risk factors for cardiovascular disease in elderly Jordanians. Lifestyle changes and regular monitoring of blood pressure, lipids, and glucose are recommended to prevent these conditions.

Area of Science:

  • Cardiology
  • Endocrinology
  • Geriatrics

Background:

  • Hypertension (HTN), dyslipidemia, and hyperglycemia are significant risk factors for cardiovascular disease (CVD) in the elderly Jordanian population.
  • These conditions contribute to high morbidity and mortality rates among older adults in Jordan.
  • Understanding the interplay of these factors is crucial for effective CVD prevention strategies.

Purpose of the Study:

  • To evaluate serum lipid and glucose profiles in hypertensive patients compared to normotensive controls.
  • To identify risk factors associated with hypertension in the elderly Jordanian population.
  • To inform future strategies for preventing dyslipidemia, hyperglycemia, and subsequent hypertension.

Main Methods:

  • A cross-sectional study involving 200 participants (111 hypertensive, 89 normotensive) in North Jordan.
  • Data collection included sociodemographic factors, anthropometric measurements, blood pressure, and biochemical profiles (total cholesterol, triglyceride, LDL, HDL, fasting blood sugar).
  • Study conducted between June and October 2017.

Main Results:

  • Hypertensive subjects exhibited higher serum levels of total cholesterol, triglycerides, LDL, and fasting blood sugar, with lower HDL levels compared to normotensives (p < 0.01).
  • No significant differences in age, waist circumference, waist-to-height ratio, or BMI were observed between groups.
  • Overweight/obesity, abdominal obesity (WHtR), hyperglycemia, hypertriglyceridemia, and low HDL were identified as risk factors for hypertension.

Conclusions:

  • Future strategies should focus on preventing dyslipidemia and hyperglycemia to mitigate hypertension risk.
  • Lifestyle modifications and medical management are essential for risk factor control.
  • Regular monitoring of blood pressure, lipid, and glucose profiles is recommended for hypertensive patients within primary healthcare settings to prevent non-communicable diseases.
Abstract

Keywords:
Cardiovascular diseasesHyperglycemiaHypertensionLipid profileMetabolic syndrome

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