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LSG vs MGB-OAGB-3 Year Follow-up Data: a Randomised Control Trial.

S Shivakumar1, Om Tantia2, Ghanshyam Goyal1

  • 1Department of Minimal Access & Bariatric Surgery, ILS Hospitals, DD-6, Sector 1, Salt Lake City, Kolkata, West Bengal, 700064, India.

Obesity Surgery
|April 22, 2018
PubMed
Summary
This summary is machine-generated.

One anastomosis gastric bypass (MGB-OAGB) and laparoscopic sleeve gastrectomy (LSG) showed similar weight loss and hypertension remission after 3 years. MGB-OAGB offered slightly better diabetes remission and quality of life, though not statistically significant.

Keywords:
Bariatric analysis reporting and outcome system (BAROS)Gastro-esophageal reflux disease (GERD)Hypertension (HTN)Laparoscopic sleeve gastrectomy (LSG)One anastomosis gastric bypass (MGB-OAGB)Percentage actual weight loss (%AWL)Percentage excess weight loss (%EWL)Quality of life (QOL)Randomised control trial (RCT)Roux-En-Y gastric bypass (RYGB)Type 2 diabetes mellitus(T2DM)

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Area of Science:

  • Bariatric surgery outcomes
  • Metabolic and bariatric surgery comparison
  • Surgical treatment for obesity and comorbidities

Background:

  • Obesity is a global health crisis requiring effective long-term management strategies.
  • Bariatric surgical procedures like laparoscopic sleeve gastrectomy (LSG) and one anastomosis gastric bypass (MGB-OAGB) are established treatments.
  • Comparative data on the long-term efficacy and safety of these procedures are crucial for clinical decision-making.

Purpose of the Study:

  • To compare the 3-year follow-up outcomes of MGB-OAGB and LSG.
  • To evaluate differences in weight loss, complication rates, comorbidity resolution, and quality of life.
  • To provide evidence for the comparative effectiveness of these two bariatric procedures.

Main Methods:

  • A prospective randomized controlled trial was conducted between 2012 and 2015.
  • 100 patients underwent LSG and 101 patients underwent MGB-OAGB.
  • Outcomes including percentage of excess weight loss (%EWL), complication rates, comorbidity resolution (diabetes, hypertension), and quality of life (BAROS score) were assessed at 3-year follow-up.

Main Results:

  • At 3 years, average %EWL was 61.15% for LSG and 66.48% for MGB-OAGB (statistically insignificant difference).
  • Diabetes remission rates were 81.82% for LSG and 89.13% for MGB-OAGB; hypertension remission rates were 72.22% for LSG and 74% for MGB-OAGB.
  • MGB-OAGB patients reported a better quality of life, indicated by higher BAROS scores (6.96 vs 6.03 with comorbidities; 4.34 vs 3.86 without comorbidities).

Conclusions:

  • No significant differences were observed between LSG and MGB-OAGB in %EWL and hypertension remission at 36 months.
  • MGB-OAGB demonstrated higher, though statistically insignificant, type 2 diabetes mellitus remission rates compared to LSG.
  • MGB-OAGB patients, particularly those with comorbidities, experienced a better quality of life post-surgery compared to LSG patients.