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Updated: Feb 11, 2026

Retzius-Sparing Robot-Assisted Radical Prostatectomy
Published on: May 19, 2022
Open radical prostatectomy after transurethral resection: perioperative, functional, oncologic outcomes
Charalampos Fragkoulis1, Athanasios Pappas, Georgios Theocharis
1Department of Urology, Athens General Hospital 'G. Gennimatas', Athens, Greece.
Radical retropubic prostatectomy (RRP) after transurethral resection of the prostate (TURP) is safe, with preserved continence but potentially compromised erectile function. Oncologic outcomes remain unaffected, though the procedure is more demanding.
Area of Science:
- Urology
- Oncology
- Surgical Outcomes
Background:
- Radical retropubic prostatectomy (RRP) is a standard treatment for prostate cancer.
- Transurethral resection of the prostate (TURP) is a common procedure for benign prostatic hyperplasia.
- The impact of prior TURP on RRP outcomes requires further investigation.
Purpose of the Study:
- To compare perioperative, functional, and oncologic outcomes of RRP in patients with and without a history of TURP.
- To assess the safety and feasibility of RRP following TURP.
Main Methods:
- Retrospective matched-cohort study of 70 patients (35 with prior TURP, 35 without).
- Matching criteria included age, BMI, PSA, Gleason score, prostate volume, pathological stage, and surgical technique.
- Follow-up was conducted for one year post-RRP.
Main Results:
- No significant differences in functional or oncologic outcomes between groups.
- RRP after TURP was more technically demanding, with increased operative time and blood loss.
- Later catheter removal was observed in the prior TURP group.
Conclusions:
- RRP following TURP is a safe procedure with preserved oncologic outcomes and continence.
- Erectile function may be compromised in patients with a history of TURP.
- Surgeons must be aware of potential intraoperative challenges when performing RRP after TURP.
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