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Updated: Feb 11, 2026

Intranasal Administration of CNS Therapeutics to Awake Mice
Published on: April 8, 2013
[Temporary approval for intranasal naloxone: Setting up in a French addiction center]
Thomas Barré1, Florence Vorspan2, Maeva Fortias1
1Département de psychiatrie et de médecine addictologique, hôpital Fernand Widal, AP-HP, 200, rue du faubourg-Saint-Denis, 75010 Paris, France.
Abstract:
Intranasal naloxone aims at preventing opioid overdose related deaths in active drug users. In France, it has been available since July 2016 through a temporary approval which requires a hospital-based pharmacy and a nominative registration of each patient. We present the characteristics of the first patients who could receive this prescription in our hospital-based addiction center and how they used naloxone during follow-up. Results favor a larger dispensing of naloxone. Patients' as well as peers' and families' education is needed.
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