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Updated: Feb 11, 2026

Studying Proteolysis of Cyclin B at the Single Cell Level in Whole Cell Populations
Published on: September 17, 2012
The Dual Face of Cyclin B1
Arp Schnittger1, Lieven De Veylder2
1Department of Developmental Biology, University of Hamburg, Hamburg, Germany.
Abstract:
Although widely used as a marker for cell proliferation, CYCB1;1 expression is also strongly induced in cells that suffer from DNA damage. Recently, this enigmatic dual expression pattern has been resolved by proving that CYCB1;1 promotes DNA repair. This has consequences for using CYCB1;1 as a cell cycle reporter.
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