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Updated: Feb 11, 2026

A Stably Established Two-Point Injection of Lysophosphatidylcholine-Induced Focal Demyelination Model in Mice
Published on: May 11, 2022
Corpus callosum demyelination associated with acquired stuttering
Barbara McElwee Decker1, Barry Guitar2, Andrew Solomon1
1Department of Neurological Sciences, University of Vermont Medical Center, Burlington, Vermont, USA.
Abstract:
Compared with developmental stuttering, adult onset acquired stuttering is rare. However, several case reports describe acquired stuttering and an association with callosal pathology. Interestingly, these cases share a neuroanatomical localisation also demonstrated in developmental stuttering. We present a case of adult onset acquired stuttering associated with inflammatory demyelination within the corpus callosum. This patient's disfluency improved after the initiation of immunomodulatory therapy.
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