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Published on: December 14, 2014
Placebo Analgesia in Rodents: Current and Future Research
Asaf Keller1, Titilola Akintola2, Luana Colloca3
1Program in Neuroscience, University of Maryland School of Medicine, Baltimore, MD, United States; Center to Advance Chronic Pain Research, University of Maryland, Baltimore, MD, United States.
Abstract:
The investigation of placebo effects in animal pain models has received less attention than human research. This may be related to a number of difficulties, including the fact that animals lack the ability to use language and establish expectancies verbally, that animals cannot report and rate the extent to which they experience pain, and the inadequacy of current models of pain. Here, we describe the relatively small number of studies that have been published, communicating the opportunities and excitement of this research. We critically discuss pitfalls and limitations with the hope that this will advance future animal placebo-related research.
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