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Updated: Feb 11, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Endoscopic versus Microscopic Pituitary Adenoma Surgery: An Institutional Experience
Hanuman Prasad Prajapati1, Shashi Kant Jain1, Virendra D Sinha1
1Department of Neurosurgery, SMS Medical College and Hospital, Jaipur, Rajasthan, India.
Endoscopic pituitary adenoma excision offers better tumor removal rates and shorter operative times compared to microscopic techniques. This minimally invasive approach also leads to reduced blood loss and fewer complications, improving patient outcomes.
Area of Science:
- Neurosurgery
- Endoscopic Surgery
- Pituitary Adenoma Treatment
Background:
- Pituitary adenomas are common intracranial tumors requiring surgical intervention.
- Transsphenoidal surgery is a primary surgical approach for pituitary adenoma excision.
- Comparing endoscopic and microscopic techniques is crucial for optimizing surgical outcomes.
Purpose of the Study:
- To compare the efficacy of endoscopic versus microscopic excision of pituitary adenoma.
- To evaluate the advantages and disadvantages of each surgical approach.
Main Methods:
- Prospective study involving 30 patients with pituitary adenoma.
- Patients underwent transsphenoidal surgery, either endoscopic (17) or microscopic (13).
- Data collected included demographics, symptoms, hospital stay, hormone status, resection extent, and complications.
Main Results:
- Endoscopic excision achieved complete tumor removal in 64.71% of patients, versus 46.15% for microscopic.
- Mean operative time and blood loss were significantly lower in the endoscopic group.
- Postoperative sinusitis occurred in 5.88% of endoscopic cases compared to 15.38% of microscopic cases.
Conclusions:
- The endoscopic approach provides a wider surgical field and better visualization, facilitating tumor distinction.
- Endoscopic pituitary adenoma excision results in greater tumor removal, reduced operative time, and fewer complications.
- This technique may lead to earlier hospital discharge and improved patient recovery.
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