Novel Imaging Modalities for Human Embryology and Applications in Education

Advances in imaging technology and development have recently enabled high-resolution three-dimensional (3D) imaging of embryos and fetuses. Embryos and fetuses stored at the Congenital Anomaly Research Center (Kyoto Collection of Human Embryos, Kyoto, Japan) were imaged using multiple modalities including magnetic resonance imaging, episcopic fluorescence image capture, and X-ray computed tomography, both in absorption and phase-contrasted configurations. Using the acquired images, 3D computer graphics were generated and a movie was created to gain further insight into understanding the developmental process. For educational purposes, self-learning materials were also produced. The present review article briefly discusses each project and the results of imaging studies performed using specimens from the Kyoto Collection of Human Embryos. Anat Rec, 301:1004-1011, 2018. © 2018 Wiley Periodicals, Inc.