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Updated: Feb 11, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
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Evaluating the utility of autoantibodies for disease activity and relapse in giant cell arteritis

T Kuret1, K Lakota1,2, A Hočevar1

  • 1Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Journal of Biological Regulators and Homeostatic Agents
|April 25, 2018
PubMed

Insights

This review examines autoantibodies in giant cell arteritis (GCA), finding anti-ferritin antibodies highly prevalent. Combining these with antiphospholipid and antineutrophil cytoplasmic antibodies may aid in detecting GCA relapse.

Area of Science:

  • Immunology
  • Rheumatology
  • Vasculitis Research

Background:

  • Giant cell arteritis (GCA) is associated with various autoantibodies, but their clinical utility requires updated evaluation.
  • Existing reviews lack current data on autoantibody detection methods and their significance in GCA management.

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