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Updated: Feb 11, 2026

Author Spotlight: Unraveling the Interplay Between Trichoderma stromaticum and the Mammalian Immune System
Published on: October 20, 2023
Trichodermatides E and F from fungus Trichoderma applanatum
Lin Chen1,2,3, Guang-Wei Wu1, Dong Liu4
1a State Key Laboratory of Mycology, Institute of Microbiology , Chinese Academy of Sciences , Beijing 100101 , China.
Abstract:
Two new polyketide derivatives, trichodermatides E (1) and F (2), are unprecedented examples of a polyketide with 6/6/6/6 tetracyclic skeleton, together with five known analogs koninginin B (3), koninginin D (4), 7-O-methylkoninginin D (5), koninginins E and F (6-7), were isolated from the plant endophytic fungus Trichoderma applanatum. The structures of these two compounds were determined by NMR data and HR-ESI-MS analysis. The putative biosynthesis of compounds 1-7 was presented.

