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Related Concept Videos

Lung Capacity01:47

Lung Capacity

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The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
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Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors01:28

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Phosphodiesterase 5 (PDE5) inhibitors are potent enzymes that function to hydrolyze cyclic nucleotides to their corresponding 5' monophosphates. Their unique biochemical properties have been applied in treating Pulmonary Arterial Hypertension (PAH).
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
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Angle of Twist: Problem Solving01:13

Angle of Twist: Problem Solving

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An electric motor applies a torque of 700 N·m to an aluminum shaft, triggering a stable rotation. Two pulleys, B and C, are subjected to torques of 300 N·m and 400 N·m, respectively. The modulus of rigidity is provided as 25 GPa. With the knowledge of the length and diameter of each segment, the twist angle between the two pulleys can be computed. First, a section cut is made between pulleys B and C, and the cut cross-section is analyzed using a free-body diagram. Given that the torque...
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Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists01:18

Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists

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Endothelins (ETs) are potent vasoactive peptides critical in the human body's various physiological and pathological processes. One of the most promising therapeutic strategies for treating pulmonary arterial hypertension (PAH) involves counteracting the effects of these endothelins using a class of drugs known as endothelin receptor antagonists.
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Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists01:23

Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists

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Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
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Angle of Twist - Elastic Range01:13

Angle of Twist - Elastic Range

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Consider a cylindrical shaft with a length denoted by L and a consistent cross-sectional radius referred to as r. This shaft undergoes a torque at the free end. The highest shearing strain within the shaft is directly proportional to the twist angle and the radial distance from the shaft axis. When the shaft behaves elastically, this shearing strain can be articulated using variables such as the applied torque, radial distance, the polar moment of inertia, and the modulus of rigidity. By...
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Updated: Feb 11, 2026

Orthotopic Left Lung Transplantation in Rats
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Orthotopic Left Lung Transplantation in Rats

Published on: July 3, 2025

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Pulmonary artery twisting during lung transplantation.

Andrew Lichliter1, Joseph Oros1, Louba Laurie1

  • 1Department of Radiology, Baylor University Medical Center at Dallas, Dallas, Texas.

Proceedings (Baylor University. Medical Center)
|April 25, 2018
PubMed
Summary

Pulmonary artery twisting is a critical early complication after lung transplant. Recognizing its specific imaging signs is vital for prompt diagnosis and improved patient outcomes.

Keywords:
Imaginglung transplantationpulmonary artery twisting

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Area of Science:

  • Cardiothoracic Radiology
  • Transplant Surgery

Background:

  • Complications following lung transplantation often present with nonspecific clinical and imaging findings.
  • Understanding the temporal progression of complications is crucial for accurate radiologic interpretation.

Observation:

  • Pulmonary artery twisting is an underrecognized complication in the immediate and early postoperative phases of lung transplantation.
  • This specific complication demands early recognition due to its significant impact on patient morbidity and mortality.

Findings:

  • The case study illustrates key imaging manifestations of the pulmonary artery relevant to postoperative complications.
  • Radiologists must be aware of the potential for vascular anomalies like twisting in the early post-transplant period.

Implications:

  • Early identification of pulmonary artery twisting can lead to timely intervention, potentially reducing severe outcomes.
  • Enhanced awareness of this complication among radiologists and surgeons may improve lung transplant patient management.