Related Experiment Video
Updated: Feb 11, 2026

Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction
Published on: April 1, 2019
Determining the optimal parameters of 420-nm intense pulsed light on Trichophyton rubrum growth in vitro
Hao Huang1, Hongfeng Tang2, Meiling Huang1
1Department of Dermatology, Shunde Hospital, Southern Medical University, Foshan, 528300, China.
Abstract:
The effect of and the optimal parameters for intense pulsed light (IPL) with a 420-nm filter on an isolate of the fungus Trichophyton rubrum (T. rubrum) were examined in vitro. Colonies of T. rubrum were irradiated by using 420-nm IPL with various pulse numbers and energies. Colony areas were photographed and compared with those of untreated colonies to assess growth inhibition. Statistically significant inhibition of T. rubrum growth was detected in colonies treated with 12 pulses of greater than or equal to 12 J/cm2. The optimal parameters of 420-nm IPL were 12 pulses of 12 J/cm2. However, more in vitro and in vivo studies are necessary to investigate and explore this mechanism to determine whether IPL would have a potential use in the treatment of fungal infections of the skin.
More Related Videos
Related Concept Videos
Determination of Multiple Dosing Parameters: Loading and Maintenance Doses
Determination of Multiple Dosing Parameters: Steady-State, Minimum and Maximum Concentrations
Pulse
The pulse serves as a clinical...
Pulse
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls...
Light Acquisition
Sound Intensity

