Related Experiment Video
Updated: Feb 11, 2026

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse
Published on: March 8, 2013
Lymphatic imaging and intervention in a pediatric population: Anesthetic considerations
David R Jobes1, Lauren A Brown1, Yoav Dori2
1Department of Anesthesiology and Critical Care, Division of Cardiothoracic Anesthesiology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
New lymphatic imaging and intervention techniques aid severe pediatric lymphatic disorders. General anesthesia for these procedures in high-risk children requires intensive care monitoring, with 25% experiencing complications.
Area of Science:
- Pediatric Anesthesiology
- Interventional Radiology
- Lymphatic Imaging and Intervention
Background:
- Severe pediatric lymphatic disorders often require advanced diagnostic and therapeutic interventions.
- These procedures necessitate general anesthesia due to immobility requirements for accurate catheter/needle placement and patient comfort.
- Managing medically complex pediatric patients under anesthesia presents significant logistical and medical challenges.
Purpose of the Study:
- To review the anesthetic management and outcomes of pediatric patients undergoing lymphatic imaging and intervention.
- To evaluate the safety and feasibility of these procedures in a specialized pediatric center.
- To identify complications and care escalation patterns in this high-risk population.
Main Methods:
- Retrospective review of a one-year cohort of pediatric patients undergoing lymphatic procedures.
- Data collected included patient demographics, comorbidities, anesthetic details, concurrent procedures, and intensive care unit (ICU) outcomes.
- All patients received general anesthesia with paralysis and controlled ventilation.
Main Results:
- 106 anesthetics were administered to 68 pediatric patients (4 days to 17 years).
- 98% of patients were American Society of Anesthesiologists (ASA) class 3 or 4, with 79.4% having significant comorbidities.
- 76% of procedures involved concurrent interventions; 25% of patients experienced complications within 24 hours of ICU admission.
Conclusions:
- Improved lymphatic access and Dynamic Contrast-enhanced Magnetic Resonance Lymphangiography enable treatment for severe lymphatic disorders.
- Anesthetic management for these high-risk pediatric patients is complex, often involving multiple procedures.
- Intensive care observation is crucial for managing potential complications in the immediate postoperative period.
More Related Videos
Related Concept Videos
Development of the Lymphatic System
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
Nursing Interventions I: Taxonomy of Nursing Interventions
A nursing intervention is a treatment or action based on scientific concepts and knowledge from the nursing, behavioral, and physical sciences. Identifying and prioritizing nursing interventions based on the desired outcome...
Design Consideration
The factor of safety is another key...
Nursing Interventions II: Selecting and Classifying the Nursing Interventions
Conservation of Small Populations
What is Population Genetics?

