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Updated: Feb 11, 2026

Surgical Models of Gastroesophageal Reflux with Mice
Published on: August 25, 2015
Gastric reflux: the therapeutical role of Marial®
S E Aragona1, G Mereghetti1, G Ciprandi2
1Center of Regenerative Medicine, Humanitas Mater Domini, Castellanza (VA), Italy
Abstract:
The worldwide relevance of gastroesophageal reflux disease (GERD) has had a considerable increase in recent years. The guidelines for the diagnosis and treatment of GERD are well consolidated and continuously updated. Recently, the extra-esophageal manifestations of reflux have been considered from a multidisciplinary point of view, so the symptoms of the laryngo-pharyngeal reflux (LPR) have been precisely defined. At present, a new Medical Compound (Marial®) has the indication for the treatment of both GERD and LPR. Clinical experience has initially confirmed its effectiveness in both disorders.
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