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The Clinical Value of Diffusion-Weighted Magnetic Resonance Imaging in Diabetic Foot Infection

Mehmet Ali Eren, Ekrem Karakaş, Ayşe Nur Torun

    Journal of the American Podiatric Medical Association
    |April 25, 2018
    PubMed
    Abstract

    Insights

    Diffusion-weighted imaging (DWI) aids in diagnosing osteomyelitis in diabetic foot ulcers (DFU). Lower apparent diffusion coefficient (ADC) values in bone indicate infection, making DWI a valuable, contrast-free MRI tool.

    Area of Science:

    • Radiology
    • Diabetology
    • Orthopedics

    Background:

    • Diabetic foot osteomyelitis is a common complication leading to amputation.
    • Early and accurate diagnosis is crucial for limb salvage.

    Purpose of the Study:

    • To evaluate the diagnostic role of diffusion-weighted magnetic resonance imaging (DWI) for osteomyelitis in diabetic foot ulcers (DFU).

    Main Methods:

    • Thirty patients with type 2 diabetes and DFU underwent conventional MRI and DWI.
    • Apparent diffusion coefficient (ADC) values were measured in bone and adjacent soft tissues.

    Main Results:

    • Patients with osteomyelitis showed significantly lower bone ADC values (P = .022) and higher erythrocyte sedimentation rates (P = .014).
    • Bone ADC values were significantly lower than soft tissue ADC values in patients with osteomyelitis (P = .04).

    Conclusions:

    • DWI offers a rapid, contrast-agent-free method for evaluating DFU.
    • DWI can serve as an alternative diagnostic tool for detecting osteomyelitis in diabetic foot ulcers.

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