Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What are Populations and Communities?00:30

What are Populations and Communities?

38.0K
Overview
38.0K
Community Based Intervention01:30

Community Based Intervention

487
Community-based interventions in mental health represent a paradigm shift from institution-centered care to treatments embedded within the fabric of local communities. By prioritizing inclusion and leveraging existing societal structures, this approach fosters a supportive environment conducive to addressing mental health challenges while promoting individual dignity and agency.
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
487
Integration by Parts: Indefinite Integrals01:26

Integration by Parts: Indefinite Integrals

230
Integration by parts is a fundamental technique in calculus for evaluating integrals involving the product of two functions. It is particularly useful when direct integration is not feasible. The method is based on the product rule for differentiation, which states that the derivative of a product equals the derivative of the first function times the second, plus the first function times the derivative of the second. By integrating this identity and rearranging terms, the integration by parts...
230
Integration by Parts: Definite Integrals01:23

Integration by Parts: Definite Integrals

91
Definite integrals involving the product of two functions over a fixed interval can be evaluated using integration by parts. This method rewrites the integral as the difference of a product evaluated at the endpoints and a remaining definite integral that is often simpler to compute.A representative example is the definite integral of the inverse tangent function. Since there is no direct integration formula for arctan ⁡x, the integrand is rewritten as a product of arctan⁡ x and the...
91
ATP Driven Pumps I: An Overview01:27

ATP Driven Pumps I: An Overview

9.9K
ATP-driven pumps, also known as transport ATPases, are integral membrane proteins. They have binding sites for ATP located on the membrane's cytosolic side and the ion-conducting domain in the transmembrane region. These pumps use the free energy released from ATP hydrolysis to move the solutes across cell membranes against an electrochemical gradient.
There are four main types of ATP-driven pumps - P-type, V-type, F-type, and ABC transporter. All these pumps are of varying complexities and...
9.9K
Xylem and Transpiration-driven Transport of Resources02:03

Xylem and Transpiration-driven Transport of Resources

26.9K
The xylem of vascular plants distributes water and dissolved minerals that are taken up by the roots to the rest of the plant. The cells that transport xylem sap are dead upon maturity, and the movement of xylem sap is a passive process.
26.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multilayer network approaches to omics data integration in digital twins for cancer research.

Frontiers in systems biology·2026
Same author

TabularQual: A spreadsheet-based format for annotating and curating logical models in SBML-qual.

bioRxiv : the preprint server for biology·2026
Same author

Distinct Molecular Pathways Supporting Sjögren Disease Clusters and Disease Progression.

Arthritis & rheumatology (Hoboken, N.J.)·2026
Same author

Suggested experimental design and computational modeling to infer single-cell lipid dynamics from a single destructive measurement.

iScience·2026
Same author

The SjD Map: an interactive pathway tour into Sjögren's disease signalling mechanisms.

NPJ systems biology and applications·2026
Same author

From FAIR to CURE: guidelines for computational models of biological systems.

NPJ systems biology and applications·2026
Same journal

STED: flexible cross-modal topic modeling infers cell-type-specific regulatory landscapes from bulk epigenomics.

Briefings in bioinformatics·2026
Same journal

A knowledge-guided deep learning framework for quantitative nucleic acid testing.

Briefings in bioinformatics·2026
Same journal

Optimal transport for label transfer in single-cell multi-omics integration.

Briefings in bioinformatics·2026
Same journal

Continuous multi-omics pathway enrichment analysis resolves hidden functional heterogeneity.

Briefings in bioinformatics·2026
Same journal

Evaluating completeness, coherence, and consistency of genome-scale function annotations.

Briefings in bioinformatics·2026
Same journal

Transformers for single-cell RNA sequencing: a survey.

Briefings in bioinformatics·2026
See all related articles

Related Experiment Video

Updated: Feb 11, 2026

Parasite Induced Genetically Driven Autoimmune Chagas Heart Disease in the Chicken Model
09:23

Parasite Induced Genetically Driven Autoimmune Chagas Heart Disease in the Chicken Model

Published on: July 29, 2012

14.4K

Community-driven roadmap for integrated disease maps.

Marek Ostaszewski1, Stephan Gebel1, Inna Kuperstein2

  • 1Luxembourg Centre for Systems Biomedicine, Universite du Luxembourg, 7 Avenue des Hauts-Fourneaux, L-4362 Esch-sur-Alzette, Luxembourg.

Briefings in Bioinformatics
|April 25, 2018
PubMed
Summary
This summary is machine-generated.

The Disease Maps Project creates curated, user-friendly platforms for disease knowledge, focusing on interconnected biological networks. Future development includes standardized maps and mathematical models to aid clinical decisions and drug discovery.

Keywords:
biocurationdisease mapsknowledge repositorymathematical modelingmolecular biologypathway representationtranslational medicine

More Related Videos

Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community
08:53

Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community

Published on: May 31, 2019

5.8K
Mapping Dysfunctional Protein-Protein Interactions in Disease
09:39

Mapping Dysfunctional Protein-Protein Interactions in Disease

Published on: October 24, 2025

881

Related Experiment Videos

Last Updated: Feb 11, 2026

Parasite Induced Genetically Driven Autoimmune Chagas Heart Disease in the Chicken Model
09:23

Parasite Induced Genetically Driven Autoimmune Chagas Heart Disease in the Chicken Model

Published on: July 29, 2012

14.4K
Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community
08:53

Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community

Published on: May 31, 2019

5.8K
Mapping Dysfunctional Protein-Protein Interactions in Disease
09:39

Mapping Dysfunctional Protein-Protein Interactions in Disease

Published on: October 24, 2025

881

Area of Science:

  • Systems Biomedicine
  • Computational Biology
  • Disease Modeling

Background:

  • The Disease Maps Project fosters collaboration among scientific and clinical groups.
  • It aims to develop an integrated, curated, and user-friendly platform for disease-related knowledge.
  • Disease maps focus on interconnected signaling, metabolic, and gene regulatory networks in standard formats.

Purpose of the Study:

  • To summarize the 2nd Disease Maps Community meeting and outline future development milestones.
  • To highlight the creation and maintenance of standardized disease maps.
  • To discuss mathematical modeling for predicting disease comorbidity, drug response, and drug repositioning.

Main Methods:

  • Expert curation of disease maps to ensure coverage of key disease hallmarks and relevant knowledge.
  • Development of computer-readable formats for disease maps.
  • Community meeting to discuss progress, challenges, and future directions.

Main Results:

  • Key topics and outcomes from the 2nd Disease Maps Community meeting were highlighted.
  • Milestones for future development include standardized map creation, sharing common disease mechanisms, complexity management, and web exploration tools.
  • Mathematical modeling approaches were discussed as a primary goal for generating interpretable representations.

Conclusions:

  • Disease maps serve as a compendium of knowledge, facilitate hypothesis generation, and provide a scaffold for predictive mathematical models.
  • Future development focuses on standardization, modularity, technical solutions for complexity, and advanced web tools.
  • The ultimate goal is to support clinical decisions through data-driven insights and predictive modeling.