Related Experiment Video
Updated: Feb 11, 2026

Isolation Method for Long-Term and Short-Term Hematopoietic Stem Cells
Published on: May 19, 2023
FAIR principles and the IEDB: short-term improvements and a long-term vision of OBO-foundry mediated
Randi Vita1, James A Overton1, Christopher J Mungall2
1La Jolla Institute for Allergy and Immunology, Division of Vaccine Discovery and Center for Emerging Diseases and Biodefense, 9420 Athena Circle, La Jolla, CA 92037, USA.
Abstract:
The Immune Epitope Database (IEDB), at www.iedb.org, has the mission to make published experimental data relating to the recognition of immune epitopes easily available to the scientific public. By presenting curated data in a searchable database, we have liberated it from the tables and figures of journal articles, making it more accessible and usable by immunologists. Recently, the principles of Findability, Accessibility, Interoperability and Reusability have been formulated as goals that data repositories should meet to enhance the usefulness of their data holdings. We here examine how the IEDB complies with these principles and identify broad areas of success, but also areas for improvement. We describe short-term improvements to the IEDB that are being implemented now, as well as a long-term vision of true 'machine-actionable interoperability', which we believe will require community agreement on standardization of knowledge representation that can be built on top of the shared use of ontologies.
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