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cDNA sequence of the beta 2-subunit of human liver alcohol dehydrogenase
T Ehrig1, J P von Wartburg, B Wermuth
1Institut für Biochemie und Molekularbiologie, Universität Bern, Switzerland.
FEBS Letters
|July 4, 1988
Abstract:
A cDNA library of mRNA from a human liver expressing the beta 2-subunit of alcohol dehydrogenase was constructed in lambda gt11. One clone coding for 352 of a total of 374 amino acid residues of the beta 2-subunit was isolated. The sequence differed from that of the beta 1-subunit at one nucleotide position resulting in an Arg/His exchange at position 47 of the peptide chain, in agreement with data from protein sequence analysis [(1984) FEBS Lett. 173, 360-366].