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Related Experiment Video

Updated: Jun 10, 2026

Fabricating Optical-quality Glass Surfaces to Study Macrophage Fusion

Fabricating Optical-quality Glass Surfaces to Study Macrophage Fusion

Published on: March 14, 2018

Fusogens.

Nadav Segev¹, Ori Avinoam¹, Benjamin Podbilewicz²

¹Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.

Current Biology : CB

|April 25, 2018

Summary

This study introduces fusogens, proteins crucial for membrane fusion, and explores their diverse physiological roles. Understanding these proteins is key to various biological processes.

Area of Science:

Molecular Biology
Cell Biology
Biochemistry

Background:

Membrane fusion is a fundamental biological process.
Proteins mediating membrane fusion are essential for cellular functions.

Purpose of the Study:

To introduce and define fusogens, the proteins responsible for membrane fusion.
To discuss the diverse physiological functions of fusogens.

Main Methods:

Literature review and synthesis of existing research on fusogens.
Analysis of protein structures and functions related to membrane fusion.

Main Results:

Fusogens are identified as key regulators of membrane fusion.
Various physiological roles of fusogens are elucidated, including viral entry and intracellular transport.

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Detergent-free Ultrafast Reconstitution of Membrane Proteins into Lipid Bilayers Using Fusogenic Complementary-charged Proteoliposomes.

Detergent-free Ultrafast Reconstitution of Membrane Proteins into Lipid Bilayers Using Fusogenic Complementary-charged Proteoliposomes.

Published on: April 5, 2018

Synthesis, Functionalization, and Characterization of Fusogenic Porous Silicon Nanoparticles for Oligonucleotide Delivery

Synthesis, Functionalization, and Characterization of Fusogenic Porous Silicon Nanoparticles for Oligonucleotide Delivery

Published on: April 16, 2019

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Last Updated: Jun 10, 2026

Fabricating Optical-quality Glass Surfaces to Study Macrophage Fusion

Fabricating Optical-quality Glass Surfaces to Study Macrophage Fusion

Published on: March 14, 2018

Detergent-free Ultrafast Reconstitution of Membrane Proteins into Lipid Bilayers Using Fusogenic Complementary-charged Proteoliposomes.

Detergent-free Ultrafast Reconstitution of Membrane Proteins into Lipid Bilayers Using Fusogenic Complementary-charged Proteoliposomes.

Published on: April 5, 2018

Synthesis, Functionalization, and Characterization of Fusogenic Porous Silicon Nanoparticles for Oligonucleotide Delivery

Synthesis, Functionalization, and Characterization of Fusogenic Porous Silicon Nanoparticles for Oligonucleotide Delivery

Published on: April 16, 2019

Conclusions:

Fusogens are critical proteins with wide-ranging biological importance.
Further research into fusogens can unlock new therapeutic targets.